Recombinant Human EHMT2 293 Cell Lysate
Cat.No. : | EHMT2-6684HCL |
- Specification
- Gene Information
- Related Products
Description : | Antigen standard for euchromatic histone-lysine N-methyltransferase 2 (EHMT2), transcript variant NG36/G9a-SPI is a lysate prepared from HEK293T cells transiently transfected with a TrueORF gene-carrying pCMV plasmid and then lysed in RIPA Buffer. Protein concentration was determined using a colorimetric assay. The antigen control carries a C-terminal Myc/DDK tag for detection. |
Source : | HEK 293 cells |
Species : | Human |
Components : | This product includes 3 vials: 1 vial of gene-specific cell lysate, 1 vial of control vector cell lysate, and 1 vial of loading buffer. Each lysate vial contains 0.1 mg lysate in 0.1 ml (1 mg/ml) of RIPA Buffer (50 mM Tris-HCl pH7.5, 250 mM NaCl, 5 mM EDTA, 50 mM NaF, 1% NP40). The loading buffer vial contains 0.5 ml 2X SDS Loading Buffer (125 mM Tris-Cl, pH6.8, 10% glycerol, 4% SDS, 0.002% Bromophenol blue, 5% beta-mercaptoethanol). |
Size : | 0.1 mg |
Storage Instruction : | Store at -80°C. Minimize freeze-thaw cycles. After addition of 2X SDS Loading Buffer, the lysates can be stored at -20°C. Product is guaranteed 6 months from the date of shipment. |
Applications : | ELISA, WB, IP. WB: Mix equal volume of lysates with 2X SDS Loading Buffer. Boil the mixture for 10 min before loading (for membrane protein lysates, incubate the mixture at room temperature for 30 min). Load 5 ug lysate per lane. |
Gene Name : | EHMT2 euchromatic histone-lysine N-methyltransferase 2 [ Homo sapiens ] |
Official Symbol : | EHMT2 |
Synonyms : | EHMT2; euchromatic histone-lysine N-methyltransferase 2; BAT8, C6orf30, chromosome 6 open reading frame 30 , HLA B associated transcript 8; histone-lysine N-methyltransferase EHMT2; Em:AF134726.3; G9A; KMT1C; NG36/G9a; protein G9a; H3-K9-HMTase 3; G9A histone methyltransferase; HLA-B associated transcript 8; HLA-B-associated transcript 8; lysine N-methyltransferase 1C; ankyrin repeat-containing protein; histone H3-K9 methyltransferase 3; histone-lysine N-methyltransferase, H3 lysine-9 specific 3; BAT8; GAT8; NG36; C6orf30; FLJ35547; DKFZp686H08213; |
Gene ID : | 10919 |
mRNA Refseq : | NM_006709 |
Protein Refseq : | NP_006700 |
MIM : | 604599 |
UniProt ID : | Q96KQ7 |
Chromosome Location : | 6p21.3 |
Pathway : | Gene Expression, organism-specific biosystem; Lysine degradation, organism-specific biosystem; Lysine degradation, conserved biosystem; RNA Polymerase I Promoter Clearance, organism-specific biosystem; RNA Polymerase I Transcription, organism-specific biosystem; RNA Polymerase I Transcription Initiation, organism-specific biosystem; RNA Polymerase I, RNA Polymerase III, and Mitochondrial Transcription, organism-specific biosystem; |
Function : | histone methyltransferase activity (H3-K27 specific); histone methyltransferase activity (H3-K9 specific); metal ion binding; methyltransferase activity; p53 binding; protein binding; protein-lysine N-methyltransferase activity; transferase activity; zinc ion binding; |
Products Types
◆ Recombinant Protein | ||
Ehmt2-455M | Recombinant Mouse Ehmt2 Protein, MYC/DDK-tagged | +Inquiry |
EHMT2-24H | Recombinant Human EHMT2 Protein, His-tagged | +Inquiry |
EHMT2-382H | Recombinant Human EHMT2 Protein, MYC/DDK-tagged | +Inquiry |
EHMT2-2838H | Recombinant Human EHMT2 Protein, His (Fc)-Avi-tagged | +Inquiry |
EHMT2-014H | Recombinant Human EHMT2 Protein, GST-tagged | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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Q&As (5)
Ask a questionAberrant EHMT2 expression is associated with cancer progression, contributing to altered gene expression patterns and epigenetic changes in cancer cells.
EHMT2 activity can be regulated by post-translational modifications, protein-protein interactions, and its association with cofactors and other chromatin-modifying enzymes.
Yes, EHMT2-mediated H3K9 methylation can influence the recruitment of chromatin remodeling complexes, impacting the overall chromatin structure and gene expression.
EHMT2 is involved in X-chromosome inactivation by contributing to the establishment of repressive chromatin marks on one of the X chromosomes in female cells.
The expression of EHMT2 is regulated by various factors, including cellular signaling pathways and epigenetic modifications, contributing to its dynamic role in different cellular contexts.
Customer Reviews (3)
Write a reviewThe quality of this recombined protein is unmatched, providing robust and consistent results in our assays.
Timely delivery is crucial for our lab operations, meeting our expectations.
Excellent customer service—responsive and knowledgeable staff helped us choose the most suitable recombined protein for our experiments.
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