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Recombinant Human ADHFE1 cell lysate

Cat.No. : ADHFE1-32HCL
  • Specification
  • Gene Information
  • Related Products
Description : The ADHFE1 gene encodes hydroxyacid-oxoacid transhydrogenase (EC 1.1.99.24), which is responsible for the oxidation of 4-hydroxybutyrate in mammalian tissues (Kardon et al., 2006 [PubMed 16616524]).
Species : Human
Size : 100 ul
Storage Buffer : 1X Sample Buffer (50 mM Tris-HCl, 2% SDS, 10% glycerol, 300 mM 2-mercaptoethanol, 0.01% Bromophenol blue)
Applications : Western Blot;
Gene Name : ADHFE1 alcohol dehydrogenase, iron containing, 1 [ Homo sapiens ]
Official Symbol : ADHFE1
Synonyms : ADHFE1; alcohol dehydrogenase, iron containing, 1; hydroxyacid-oxoacid transhydrogenase, mitochondrial; ADHFe1; FLJ32430; alcohol dehydrogenase 8; Fe-containing alcohol dehydrogenase 1; alcohol dehydrogenase iron-containing protein 1; HOT; ADH8; HMFT2263; MGC48605;
Gene ID : 137872
mRNA Refseq : NM_144650
Protein Refseq : NP_653251
MIM : 611083
UniProt ID : Q8IWW8
Chromosome Location : 8q12.3
Pathway : Interconversion of 2-oxoglutarate and 2-hydroxyglutarate, organism-specific biosystem; Metabolism, organism-specific biosystem; Pyruvate metabolism and Citric Acid (TCA) cycle, organism-specific biosystem; The citric acid (TCA) cycle and respiratory electron transport, organism-specific biosystem;
Function : hydroxyacid-oxoacid transhydrogenase activity; metal ion binding; oxidoreductase activity;

For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

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Q&As (10)

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Can ADHFE1 interact with other proteins or participate in protein complexes, and what are the functional implications? 02/13/2022

ADHFE1 has the potential to interact with other proteins or participate in protein complexes, indicating its involvement in complex cellular processes.

What is the subcellular localization of ADHFE1, and does it undergo any dynamic changes in response to cellular signals or stimuli? 01/22/2020

ADHFE1 exhibits a specific subcellular localization, and its dynamic changes in response to cellular signals or stimuli suggest a regulatory role in cellular processes.

How does ADHFE1 contribute to cellular metabolism, and what are its functional roles in specific biological processes? 02/17/2019

ADHFE1 plays a role in cellular metabolism and contributes to specific biological processes, highlighting its functional significance in maintaining cellular homeostasis.

What are the genetic variations or polymorphisms in the ADHFE1 gene, and how do they impact its expression or enzymatic function? 12/05/2018

Genetic variations or polymorphisms in the ADHFE1 gene provide insights into individual differences and their impact on ADHFE1 expression or enzymatic function.

Are there any post-translational modifications occurring on ADHFE1, and how do they influence its stability, activity, or interaction with other molecules? 04/01/2018

Post-translational modifications on ADHFE1 can affect its stability, enzymatic activity, or interaction with other molecules, revealing their regulatory role in its function.

Can ADHFE1 deficiency or overexpression lead to any cellular or physiological phenotypes, and if so, what are the underlying mechanisms? 03/19/2018

ADHFE1 deficiency or overexpression can lead to cellular or physiological phenotypes, highlighting its essential role and the underlying mechanisms.

Are there any known regulatory factors or cofactors that modulate the activity of ADHFE1? 03/15/2018

ADHFE1's activity can be modulated by known regulatory factors or cofactors, highlighting the complexity of its functional regulation.

What is the enzymatic activity of ADHFE1, and what are its specific substrates and products? 10/27/2017

ADHFE1 possesses enzymatic activity and catalyzes specific reactions, transforming specific substrates into products.

Can ADHFE1 be targeted or modulated pharmacologically, and what are the potential therapeutic applications? 04/24/2017

ADHFE1 represents a potential target for pharmacological modulation, offering possibilities for therapeutic interventions in relevant conditions or diseases.

What is the tissue-specific expression pattern of ADHFE1, and does it exhibit any developmental or spatial regulation? 10/29/2016

ADHFE1 shows a tissue-specific expression pattern, and its developmental or spatial regulation suggests specific roles in different tissues or stages.

Customer Reviews (2)

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Reviews
11/24/2021

    Highly efficient in directing protein translocation to specific cellular compartments.

    04/01/2021

      Displays excellent stability and compatibility with different detergents in membrane protein solubilization.

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