| Gene Name : |
AKR1C3 aldo-keto reductase family 1, member C3 (3-alpha hydroxysteroid dehydrogenase, type II) [ Homo sapiens ] |
| Official Symbol : |
AKR1C3 |
| Synonyms : |
AKR1C3; aldo-keto reductase family 1, member C3 (3-alpha hydroxysteroid dehydrogenase, type II); HSD17B5, hydroxysteroid (17 beta) dehydrogenase 5; aldo-keto reductase family 1 member C3; DDX; dihydrodiol dehydrogenase X; HAKRB; KIAA0119; PGFS; prostaglandin F synthase; indanol dehydrogenase; 3-alpha-HSD type II, brain; dihydrodiol dehydrogenase 3; chlordecone reductase homolog HAKRb; testosterone 17-beta-dehydrogenase 5; type IIb 3-alpha hydroxysteroid dehydrogenase; trans-1,2-dihydrobenzene-1,2-diol dehydrogenase; DD3; HAKRe; HA1753; HSD17B5; hluPGFS; |
| Gene ID : |
8644 |
| mRNA Refseq : |
NM_001253909 |
| Protein Refseq : |
NP_001240838 |
| MIM : |
603966 |
| UniProt ID : |
P42330 |
| Chromosome Location : |
10p15-p14 |
| Pathway : |
Arachidonic acid metabolism, organism-specific biosystem; Arachidonic acid metabolism, conserved biosystem; Metabolism of xenobiotics by cytochrome P450, organism-specific biosystem; Metabolism of xenobiotics by cytochrome P450, conserved biosystem; Steroid hormone biosynthesis, organism-specific biosystem; Steroid hormone biosynthesis, conserved biosystem; androgen biosynthesis, organism-specific biosystem; |
| Function : |
15-hydroxyprostaglandin-D dehydrogenase (NADP+) activity; alditol:NADP+ 1-oxidoreductase activity; aldo-keto reductase (NADP) activity; androsterone dehydrogenase (A-specific) activity; androsterone dehydrogenase activity; delta4-3-oxosteroid 5beta-reductase activity; dihydrotestosterone 17-beta-dehydrogenase activity; geranylgeranyl reductase activity; indanol dehydrogenase activity; ketoreductase activity; ketosteroid monooxygenase activity; oxidoreductase activity, acting on NADH or NADPH, quinone or similar compound as acceptor; phenanthrene 9,10-monooxygenase activity; prostaglandin F receptor activity; prostaglandin-F synthase activity; retinal dehydrogenase activity; retinol dehydrogenase activity; testosterone 17-beta-dehydrogenase (NAD+) activity; testosterone 17-beta-dehydrogenase (NADP+) activity; trans-1,2-dihydrobenzene-1,2-diol dehydrogenase activity; |
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