Recombinant Human ARSG cell lysate

• Cat.No.: ARSG-132HCL

Specification

• Description: Sulfatases, such as ARSG, hydrolyze sulfate esters from sulfated steroids, carbohydrates, proteoglycans, and glycolipids. They are involved in hormone biosynthesis, modulation of cell signaling, and degradation of macromolecules. This gene, a novel arylsulfatase, has activity toward pseudosubstrates including p-nitrocatechol sulfate and 4-methylumbelliferyl sulfate. Activity is competitively inhibited by phosphate. The unprocessed protein is active as a 63-kDa monomer and demonstrates an acidic pH optimum as typically seen for lysosomal sulfatases. The protein accumulates within lysosomes and is also a glycoprotein that binds specifically to mannose 6-phosphate receptors.
• Species: Human
• Size: 100 ul
• Storage Buffer: 1X Sample Buffer (50 mM Tris-HCl, 2% SDS, 10% glycerol, 300 mM 2-mercaptoethanol, 0.01% Bromophenol blue)
• Applications: Western Blot

Gene Information

• Gene Name: ARSG arylsulfatase G [ Homo sapiens ]
• Official Symbol: ARSG
• Synonyms: ARSG; arylsulfatase G; KIAA1001; ASG
• Gene ID: 22901
• mRNA Refseq: NM_014960
• Protein Refseq: NP_055775
• MIM: 610008
• UniProt ID: Q96EG1
• Chromosome Location: 17q24
• Pathway: Lysosome, organism-specific biosystem; Lysosome, conserved biosystem
• Function: arylsulfatase activity; NOT arylsulfatase activity; arylsulfatase activity; hydrolase activity; metal ion binding