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Recombinant Human ARSG cell lysate

Cat.No.: ARSG-132HCL
Description: Sulfatases, such as ARSG, hydrolyze sulfate esters from sulfated steroids, carbohydrates, proteoglycans, and glycolipids. They are involved in hormone biosynthesis, modulation of cell signaling, and degradation of macromolecules. This gene, a novel arylsulfatase, has activity toward pseudosubstrates including p-nitrocatechol sulfate and 4-methylumbelliferyl sulfate. Activity is competitively inhibited by phosphate. The unprocessed protein is active as a 63-kDa monomer and demonstrates an acidic pH optimum as typically seen for lysosomal sulfatases. The protein accumulates within lysosomes and is also a glycoprotein that binds specifically to mannose 6-phosphate receptors.
Species: Human
Size: 100 ul
Storage Buffer: 1X Sample Buffer (50 mM Tris-HCl, 2% SDS, 10% glycerol, 300 mM 2-mercaptoethanol, 0.01% Bromophenol blue)
Applications: Western Blot;
Gene Name: ARSG arylsulfatase G [ Homo sapiens ]
Official Symbol: ARSG
Synonyms: ARSG; arylsulfatase G; KIAA1001; ASG;
Gene ID: 22901
mRNA Refseq: NM_014960
Protein Refseq: NP_055775
MIM: 610008
UniProt ID: Q96EG1
Chromosome Location: 17q24
Pathway: Lysosome, organism-specific biosystem; Lysosome, conserved biosystem;
Function: arylsulfatase activity; NOT arylsulfatase activity; arylsulfatase activity; hydrolase activity; metal ion binding;

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