Cat.No.:	CA5B-265HCL
Description:	Carbonic anhydrases (CAs) are a large family of zinc metalloenzymes that catalyze the reversible hydration of carbon dioxide. They participate in a variety of biological processes, including respiration, calcification, acid-base balance, bone resorption, and the formation of aqueous humor, cerebrospinal fluid, saliva, and gastric acid. They show extensive diversity in tissue distribution and in their subcellular localization. CA VB is localized in the mitochondria and shows the highest sequence similarity to the other mitochondrial CA, CA VA. It has a wider tissue distribution than CA VA, which is restricted to the liver. The differences in tissue distribution suggest that the two mitochondrial carbonic anhydrases evolved to assume different physiologic roles.
Species:	Human
Size:	100 ul
Storage Buffer:	1X Sample Buffer (50 mM Tris-HCl, 2% SDS, 10% glycerol, 300 mM 2-mercaptoethanol, 0.01% Bromophenol blue)
Applications:	Western Blot;

Gene Name:	CA5B carbonic anhydrase VB, mitochondrial [ Homo sapiens ]
Official Symbol:	CA5B
Synonyms:	CA5B; carbonic anhydrase VB, mitochondrial; carbonic anhydrase 5B, mitochondrial; carbonic dehydratase; carbonate dehydratase VB; CA-VB; MGC39962;
Gene ID:	11238
mRNA Refseq:	NM_007220
Protein Refseq:	NP_009151
MIM:	300230
UniProt ID:	Q9Y2D0
Chromosome Location:	Xp22.1
Function:	carbonate dehydratase activity; lyase activity; metal ion binding; zinc ion binding;

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