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Recombinant Human CAMKK2 cell lysate

Cat.No.: CAMKK2-275HCL
Description: The product of this gene belongs to the Serine/Threonine protein kinase family, and to the Ca(2+)/calmodulin-dependent protein kinase subfamily. This protein plays a role in the calcium/calmodulin-dependent (CaM) kinase cascade by phosphorylating the downstream kinases CaMK1 and CaMK4. Seven transcript variants encoding six distinct isoforms have been identified for this gene. Additional splice variants have been described but their full-length nature has not been determined. The identified isoforms exhibit a distinct ability to undergo autophosphorylation and to phosphorylate the downstream kinases.
Species: Human
Size: 100 ul
Storage Buffer: 1X Sample Buffer (50 mM Tris-HCl, 2% SDS, 10% glycerol, 300 mM 2-mercaptoethanol, 0.01% Bromophenol blue)
Applications: Western Blot;
Gene Name: CAMKK2 calcium/calmodulin-dependent protein kinase kinase 2, beta [ Homo sapiens ]
Official Symbol: CAMKK2
Synonyms: CAMKK2; calcium/calmodulin-dependent protein kinase kinase 2, beta; calcium/calmodulin-dependent protein kinase kinase 2; CAMKK; CAMKKB; KIAA0787; MGC15254; caM-KK 2; caM-KK beta; CAMKK beta protein; caM-kinase kinase 2; caM-kinase kinase beta; calcium/calmodulin-dependent protein kinase beta;
Gene ID: 10645
mRNA Refseq: NM_006549
Protein Refseq: NP_006540
UniProt ID: Q96RR4
Chromosome Location: 12q24.2
Pathway: Adipocytokine signaling pathway, organism-specific biosystem; Adipocytokine signaling pathway, conserved biosystem;
Function: ATP binding; calcium ion binding; calmodulin binding; calmodulin-dependent protein kinase activity; nucleotide binding; protein tyrosine kinase activity;

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