Recombinant Human CDC14B cell lysate

• Cat.No.: CDC14B-318HCL

Specification

• Description: The protein encoded by this gene is a member of the dual specificity protein tyrosine phosphatase family. This protein is highly similar to Saccharomyces cerevisiae Cdc14, a protein tyrosine phosphatase involved in the exit of cell mitosis and initiation of DNA replication, which suggests the role in cell cycle control. This protein has been shown to interact with and dephosphorylates tumor suppressor protein p53, and is thought to regulate the function of p53. Alternative splice of this gene results in 3 transcript variants encoding distinct isoforms.
• Species: Human
• Size: 100 ul
• Storage Buffer: 1X Sample Buffer (50 mM Tris-HCl, 2% SDS, 10% glycerol, 300 mM 2-mercaptoethanol, 0.01% Bromophenol blue)
• Applications: Western Blot

Gene Information

• Gene Name: CDC14B CDC14 cell division cycle 14 homolog B (S. cerevisiae) [ Homo sapiens ]
• Official Symbol: CDC14B
• Synonyms: CDC14B; CDC14 cell division cycle 14 homolog B (S. cerevisiae); CDC14 (cell division cycle 14, S. cerevisiae) homolog B; dual specificity protein phosphatase CDC14B; Cdc14B1; Cdc14B2; CDC14B3; hCDC14B
• Gene ID: 8555
• mRNA Refseq: NM_001077181
• Protein Refseq: NP_001070649
• MIM: 603505
• UniProt ID: O60729
• Chromosome Location: 9q22.3
• Pathway: Cell cycle, organism-specific biosystem; Cell cycle, organism-specific biosystem; Cell cycle, conserved biosystem; PLK1 signaling events, organism-specific biosystem
• Function: hydrolase activity; protein serine/threonine phosphatase activity; protein tyrosine phosphatase activity; protein tyrosine/serine/threonine phosphatase activity