Recombinant Human CDC14B Protein, GST-Tagged CDC14B-0900H

Recombinant Human CDC14B Protein, GST-Tagged

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Recombinant Human CDC14B Protein, GST-Tagged

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Cat.No. : CDC14B-0900H
Product Overview : Human CDC14B full-length ORF (ENSP00000265659, 1 a.a. - 471 a.a.) recombinant protein with GST-tag at N-terminal.
Description : The protein encoded by this gene is a member of the dual specificity protein tyrosine phosphatase family. This protein is highly similar to Saccharomyces cerevisiae Cdc14, a protein tyrosine phosphatase involved in the exit of cell mitosis and initiation of DNA replication, which suggests the role in cell cycle control. This protein has been shown to interact with and dephosphorylates tumor suppressor protein p53, and is thought to regulate the function of p53. Alternative splice of this gene results in 3 transcript variants encoding distinct isoforms. [provided by RefSeq, Jul 2008]
Source : Wheat Germ
Species : Human
Tag : GST
Molecular Mass : 80.6 kDa
AA Sequence : MKRKSERRSSWAAAP PCSRRCSSTSPGVKK IRSSTQQDPRRRDPQ DDVYLDITDRLCFAI LYSRPKSASNVHYFS IDNELEYENFYADFG PLNLAMVYRYCCKIN KKLKSITMLRKKIVH FTGSDQRKQANAAFL VGCYMVIYLGRTPEE AYRILIFGETSYIPF RDAAYGSCNFYITLL DCFHAVKKAMQYGFL NFNSFNLDEYEHYEK AENGDLNWIIPDRFI AFCGPHSRARLESGY HQHSPETYIQYFKNH NVTTIIRLNKRMYDA KRFTDAGFDHHDLFF ADGSTPTDAIVKEFL DICENAEGAIAVHCK AGLGRTGTLIACYIM KHYRMTAAETIAWVR ICRPGSVIGPQQQFL VMKQTNLWLEGDYFR QKLKGQENGQHRAAF SKLLSGVDDISINGV ENQDQQEPEPYSDDD EINGVTQGDRLRALK SRRQSKTNAIPLTDG WLSQAVTFLDRLLIW LGIHKD
Applications : Enzyme-linked Immunoabsorbent Assay
Western Blot (Recombinant protein)
Antibody Production
Protein Array
Storage : Store at -80 centigrade. Aliquot to avoid repeated freezing and thawing.
Storage Buffer : 50 mM Tris-HCI, 10 mM reduced Glutathione, pH=8.0 in the elution buffer.
Quality Control Testing :

12.5% SDS-PAGE Stained with Coomassie Blue.

Gene Name : CDC14B CDC14 cell division cycle 14 homolog B (S. cerevisiae) [ Homo sapiens ]
Official Symbol : CDC14B
Synonyms : CDC14B; CDC14 cell division cycle 14 homolog B (S. cerevisiae); CDC14 (cell division cycle 14, S. cerevisiae) homolog B; dual specificity protein phosphatase CDC14B; Cdc14B1; Cdc14B2; CDC14B3; hCDC14B;
Gene ID : 8555
mRNA Refseq : NM_001077181
Protein Refseq : NP_001070649
MIM : 603505
UniProt ID : O60729

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