Recombinant Human CIDEA cell lysate

• Cat.No.: CIDEA-358HCL

Specification

• Description: This gene encodes the homolog of the mouse protein Cidea that has been shown to activate apoptosis. This activation of apoptosis is inhibited by the DNA fragmentation factor DFF45 but not by caspase inhibitors. Mice that lack functional Cidea have higher metabolic rates, higher lipolysis in brown adipose tissue and higher core body temperatures when subjected to cold. These mice are also resistant to diet-induced obesity and diabetes. This suggests that in mice this gene product plays a role in thermogenesis and lipolysis. Two alternative transcripts encoding different isoforms have been identified.
• Species: Human
• Size: 100 ul
• Storage Buffer: 1X Sample Buffer (50 mM Tris-HCl, 2% SDS, 10% glycerol, 300 mM 2-mercaptoethanol, 0.01% Bromophenol blue)
• Applications: Western Blot

Gene Information

• Gene Name: CIDEA cell death-inducing DFFA-like effector a [ Homo sapiens ]
• Official Symbol: CIDEA
• Synonyms: CIDEA; cell death-inducing DFFA-like effector a; cell death activator CIDE-A; CIDE A; CIDE-A
• Gene ID: 1149
• mRNA Refseq: NM_001279
• Protein Refseq: NP_001270
• MIM: 604440
• UniProt ID: O60543
• Chromosome Location: 18p11.21
• Function: protein homodimerization activity