Recombinant Human COL6A2 cell lysate

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Recombinant Human COL6A2 cell lysate

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Cat.No. : COL6A2-382HCL
Description : This gene encodes one of the three alpha chains of type VI collagen, a beaded filament collagen found in most connective tissues. The product of this gene contains several domains similar to von Willebrand Factor type A domains. These domains have been shown to bind extracellular matrix proteins, an interaction that explains the importance of this collagen in organizing matrix components. Mutations in this gene are associated with Bethlem myopathy and Ullrich scleroatonic muscular dystrophy. Three transcript variants have been identified for this gene.
Species : Human
Size : 100 ug
Recommended Usage : Use it directly for immuno-precipitation, or heat lysate with SDS gel loading buffer to 95°C for 5 minutes followed by rapid cooling for western blot application. If dissociating conditions are required, add reducing agent prior to heating.
Storage Buffer : In modified RIPA Lysis Buffer.
Applications : Western Blot;Immunoprecipitation;
Gene Name : COL6A2 collagen, type VI, alpha 2 [ Homo sapiens ]
Official Symbol : COL6A2
Synonyms : COL6A2; collagen, type VI, alpha 2; collagen alpha-2(VI) chain; collagen VI, alpha-2 polypeptide; human mRNA for collagen VI alpha-2 C-terminal globular domain; PP3610; FLJ46862; DKFZp586E1322;
Gene ID : 1292
mRNA Refseq : NM_001849
Protein Refseq : NP_001840
MIM : 120240
UniProt ID : P12110
Chromosome Location : 21q22.3
Pathway : Axon guidance, organism-specific biosystem; Developmental Biology, organism-specific biosystem; ECM-receptor interaction, organism-specific biosystem; ECM-receptor interaction, conserved biosystem; Focal Adhesion, organism-specific biosystem; Focal adhesion, organism-specific biosystem; Focal adhesion, conserved biosystem;
Function : extracellular matrix structural constituent; protein binding; protein binding, bridging;

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