Recombinant Human FANCE cell lysate

• Cat.No.: FANCE-594HCL

Specification

• Description: The Fanconi anemia complementation group (FANC) currently includes FANCA, FANCB, FANCC, FANCD1 (also called BRCA2), FANCD2, FANCE, FANCF, FANCG, FANCI, FANCJ (also called BRIP1), FANCL, FANCM and FANCN (also called PALB2). The previously defined group FANCH is the same as FANCA. Fanconi anemia is a genetically heterogeneous recessive disorder characterized by cytogenetic instability, hypersensitivity to DNA crosslinking agents, increased chromosomal breakage, and defective DNA repair. The members of the Fanconi anemia complementation group do not share sequence similarity; they are related by their assembly into a common nuclear protein complex. This gene encodes the protein for complementation group E.
• Species: Human
• Size: 100 ul
• Storage Buffer: 1X Sample Buffer (50 mM Tris-HCl, 2% SDS, 10% glycerol, 300 mM 2-mercaptoethanol, 0.01% Bromophenol blue)
• Applications: Western Blot

Gene Information

• Gene Name: FANCE Fanconi anemia, complementation group E [ Homo sapiens ]
• Official Symbol: FANCE
• Synonyms: FANCE; Fanconi anemia, complementation group E; FACE; Fanconi anemia group E protein; FAE
• Gene ID: 2178
• mRNA Refseq: NM_021922
• Protein Refseq: NP_068741
• MIM: 613976
• UniProt ID: Q9HB96
• Chromosome Location: 6p22-p21
• Pathway: BARD1 signaling events, organism-specific biosystem; DNA Repair, organism-specific biosystem; FA core complex, organism-specific biosystem; Fanconi Anemia pathway, organism-specific biosystem; Fanconi anemia pathway, organism-specific biosystem; Fanconi anemia pathway, conserved biosystem
• Function: molecular_function; protein binding