Recombinant Human FARP1 cell lysate

• Cat.No.: FARP1-596HCL

Specification

• Description: This gene was originally isolated through subtractive hybridization due to its increased expression in differentiated chondrocytes versus dedifferentiated chondrocytes. The resulting protein contains a predicted ezrin-like domain, a Dbl homology domain, and a pleckstrin homology domain. It is believed to be a member of the band 4.1 superfamily whose members link the cytoskeleton to the cell membrane. Two alternatively spliced transcript variants encoding distinct isoforms have been found for this gene.
• Species: Human
• Size: 100 ul
• Storage Buffer: 1X Sample Buffer (50 mM Tris-HCl, 2% SDS, 10% glycerol, 300 mM 2-mercaptoethanol, 0.01% Bromophenol blue)
• Applications: Western Blot

Gene Information

• Gene Name: FARP1 FERM, RhoGEF (ARHGEF) and pleckstrin domain protein 1 (chondrocyte-derived) [ Homo sapiens ]
• Official Symbol: FARP1
• Synonyms: FARP1; FERM, RhoGEF (ARHGEF) and pleckstrin domain protein 1 (chondrocyte-derived); FERM, RhoGEF and pleckstrin domain-containing protein 1; CDEP; MGC87400; PLEKHC2; PPP1R75; protein phosphatase 1; regulatory subunit 75; PH domain-containing family C member 2; chondrocyte-derived ezrin-like protein; protein phosphatase 1, regulatory subunit 75; pleckstrin homology domain-containing family C member 2
• Gene ID: 10160
• mRNA Refseq: NM_001001715
• Protein Refseq: NP_001001715
• MIM: 602654
• UniProt ID: Q9Y4F1
• Chromosome Location: 13q32.2
• Pathway: Regulation of RhoA activity, organism-specific biosystem
• Function: Rho guanyl-nucleotide exchange factor activity; binding; cytoskeletal protein binding; guanyl-nucleotide exchange factor activity