Recombinant Human FEV cell lysate

• Cat.No.: FEV-617HCL

Specification

• Description: This gene belongs to the ETS transcription factor family. ETS family members have a highly conserved 85-amino acid ETS domain that binds purine-rich DNA sequences. The alanine-rich C-terminus of this gene indicates that it may act as a transcription repressor. This gene is exclusively expressed in neurons of the central serotonin (5-HT) system, a system implicated in the pathogeny of such psychiatric diseases as depression, anxiety, and eating disorders. In some types of Ewing tumors, this gene is fused to the Ewing sarcoma (EWS) gene following chromosome translocations.
• Species: Human
• Size: 100 ul
• Storage Buffer: 1X Sample Buffer (50 mM Tris-HCl, 2% SDS, 10% glycerol, 300 mM 2-mercaptoethanol, 0.01% Bromophenol blue)
• Applications: Western Blot

Gene Information

• Gene Name: FEV FEV (ETS oncogene family) [ Homo sapiens ]
• Official Symbol: FEV
• Synonyms: PET-1; HSRNAFEV; protein FEV; fifth Ewing variant protein; PC12 ETS domain-containing transcription factor 1
• Gene ID: 54738
• mRNA Refseq: NM_017521
• Protein Refseq: NP_059991
• MIM: 607150
• UniProt ID: Q99581
• Chromosome Location: 2q36
• Pathway: SIDS Susceptibility Pathways, organism-specific biosystem; Transcriptional misregulation in cancer, organism-specific biosystem; Transcriptional misregulation in cancer, conserved biosystem
• Function: double-stranded DNA binding; sequence-specific DNA binding; sequence-specific DNA binding RNA polymerase II transcription factor activity