Recombinant Human GCHFR cell lysate

• Cat.No.: GCHFR-692HCL

Specification

• Description: GTP cyclohydrolase I feedback regulatory protein binds to and mediates tetrahydrobiopterin inhibition of GTP cyclohydrolase I. The regulatory protein, GCHFR, consists of a homodimer. It is postulated that GCHFR may play a role in regulating phenylalanine metabolism in the liver and in the production of biogenic amine neurotransmitters and nitric oxide.
• Species: Human
• Size: 100 ul
• Storage Buffer: 1X Sample Buffer (50 mM Tris-HCl, 2% SDS, 10% glycerol, 300 mM 2-mercaptoethanol, 0.01% Bromophenol blue)
• Applications: Western Blot

Gene Information

• Gene Name: GCHFR GTP cyclohydrolase I feedback regulator [ Homo sapiens ]
• Official Symbol: GCHFR
• Synonyms: GCHFR; GTP cyclohydrolase I feedback regulator; GTP cyclohydrolase I feedback regulatory protein; GTP cyclohydrolase 1 feedback regulatory protein; GFRP; HsT16933; P35; MGC138467; MGC138469
• Gene ID: 2644
• mRNA Refseq: NM_005258
• Protein Refseq: NP_005249
• MIM: 602437
• UniProt ID: P30047
• Chromosome Location: 15q15
• Pathway: Metabolism, organism-specific biosystem; Metabolism of nitric oxide, organism-specific biosystem; Tetrahydrobiopterin (BH4) synthesis, recycling, salvage and regulation, organism-specific biosystem; eNOS activation and regulation, organism-specific biosystem
• Function: GTP cyclohydrolase I binding; GTP-dependent protein binding; amino acid binding; enzyme inhibitor activity; protein binding