Recombinant Human HSD17B12 cell lysate

• Cat.No.: HSD17B12-818HCL

Specification

• Description: The enzyme 17-beta hydroxysteroid dehydrogenase-12 (HSD17B12) uses NADPH to reduce 3-ketoacyl-CoA to 3-hydroxyacyl-CoA during the second step of fatty acid elongation.
• Species: Human
• Size: 100 ul
• Storage Buffer: 1X Sample Buffer (50 mM Tris-HCl, 2% SDS, 10% glycerol, 300 mM 2-mercaptoethanol, 0.01% Bromophenol blue)
• Applications: Western Blot

Gene Information

• Gene Name: HSD17B12 hydroxysteroid (17-beta) dehydrogenase 12 [ Homo sapiens ]
• Official Symbol: HSD17B12
• Synonyms: HSD17B12; hydroxysteroid (17-beta) dehydrogenase 12; estradiol 17-beta-dehydrogenase 12; 3 ketoacyl CoA reductase; KAR; SDR12C1; short chain dehydrogenase/reductase family 12C; member 1; 17-beta-HSD 12; 17beta-HSD type 12; 3-ketoacyl-CoA reductase; steroid dehydrogenase homolog; 17-beta-hydroxysteroid dehydrogenase 12; short chain dehydrogenase/reductase family 12C, member 1
• Gene ID: 51144
• mRNA Refseq: NM_016142
• Protein Refseq: NP_057226
• MIM: 609574
• UniProt ID: Q53GQ0
• Chromosome Location: 11q11
• Pathway: Biosynthesis of unsaturated fatty acids, organism-specific biosystem; Biosynthesis of unsaturated fatty acids, conserved biosystem; Fatty Acyl-CoA Biosynthesis, organism-specific biosystem; Fatty acid biosynthesis, elongation, endoplasmic reticulum, organism-specific biosystem; Fatty acid biosynthesis, elongation, endoplasmic reticulum, conserved biosystem; Fatty acid elongation, organism-specific biosystem; Fatty acid elongation, conserved biosystem
• Function: collagen binding; estradiol 17-beta-dehydrogenase activity; fibronectin binding; heparin binding; nucleotide binding; oxidoreductase activity