Recombinant Human LOXL1 cell lysate

• Cat.No.: LOXL1-1028HCL

Specification

• Description: This gene encodes a member of the lysyl oxidase gene family. The prototypic member of the family is essential to the biogenesis of connective tissue, encoding an extracellular copper-dependent amine oxidase that catalyses the first step in the formation of crosslinks in collagens and elastin. A highly conserved amino acid sequence at the C-terminus end appears to be sufficient for amine oxidase activity, suggesting that each family member may retain this function. The N-terminus is poorly conserved and may impart additional roles in developmental regulation, senescence, tumor suppression, cell growth control, and chemotaxis to each member of the family.
• Species: Human
• Size: 100 ul
• Storage Buffer: 1X Sample Buffer (50 mM Tris-HCl, 2% SDS, 10% glycerol, 300 mM 2-mercaptoethanol, 0.01% Bromophenol blue)
• Applications: Western Blot

Gene Information

• Gene Name: LOXL1 lysyl oxidase-like 1 [ Homo sapiens ]
• Official Symbol: LOXL1
• Synonyms: LOXL1; lysyl oxidase-like 1; lysyl oxidase homolog 1; LOL; LOXL; lysyl oxidase-like protein 1
• Gene ID: 4016
• mRNA Refseq: NM_005576
• Protein Refseq: NP_005567
• MIM: 153456
• UniProt ID: Q08397
• Chromosome Location: 15q24-q25
• Function: copper ion binding; metal ion binding; oxidoreductase activity; oxidoreductase activity, acting on the CH-NH2 group of donors, oxygen as acceptor