Recombinant Human NAPRT1 cell lysate

• Cat.No.: NAPRT1-1165HCL

Specification

• Description: Nicotinic acid (NA; niacin) is converted by nicotinic acid phosphoribosyltransferase (NAPRT; EC 2.4.2.11) to NA mononucleotide (NaMN), which is then converted to NA adenine dinucleotide (NaAD), and finally to nicotinamide adenine dinucleotide (NAD), which serves as a coenzyme in cellular redox reactions and is an essential component of a variety of processes in cellular metabolism including response to stress (Hara et al., 2007).
• Species: Human
• Size: 100 ul
• Storage Buffer: 1X Sample Buffer (50 mM Tris-HCl, 2% SDS, 10% glycerol, 300 mM 2-mercaptoethanol, 0.01% Bromophenol blue)
• Applications: Western Blot

Gene Information

• Gene Name: NAPRT1 nicotinate phosphoribosyltransferase domain containing 1 [ Homo sapiens ]
• Official Symbol: NAPRT1
• Synonyms: NAPRT1; nicotinate phosphoribosyltransferase domain containing 1; nicotinate phosphoribosyltransferase; PP3856; NAPRTase; FHA-HIT-interacting protein; nicotinic acid phosphoribosyltransferase; nicotinate phosphoribosyltransferase domain-containing protein 1
• Gene ID: 93100
• mRNA Refseq: NM_145201
• Protein Refseq: NP_660202
• MIM: 611552
• UniProt ID: Q6XQN6
• Chromosome Location: 8q24.3
• Pathway: Metabolic pathways, organism-specific biosystem; Metabolism, organism-specific biosystem; Metabolism of vitamins and cofactors, organism-specific biosystem; Metabolism of water-soluble vitamins and cofactors, organism-specific biosystem; Nicotinamide salvaging, organism-specific biosystem; Nicotinate and nicotinamide metabolism, organism-specific biosystem; Nicotinate and nicotinamide metabolism, conserved biosystem
• Function: nicotinate phosphoribosyltransferase activity; nicotinate phosphoribosyltransferase activity; nicotinate-nucleotide diphosphorylase (carboxylating) activity; transferase activity, transferring glycosyl groups