Recombinant Human NXF3 cell lysate

• Cat.No.: NXF3-1238HCL

Specification

• Description: This gene is one member of a family of nuclear RNA export factor genes. Common domain features of this family are a noncanonical RNP-type RNA-binding domain (RBD), 4 leucine-rich repeats (LRRs), a nuclear transport factor 2 (NTF2)-like domain that allows heterodimerization with NTF2-related export protein-1 (NXT1), and a ubiquitin-associated domain that mediates interactions with nucleoporins. The LRRs and NTF2-like domains are required for export activity. Alternative splicing seems to be a common mechanism in this gene family. The encoded protein of this gene has shortened LRR and ubiquitin-associated domains and its RDB is unable to bind RNA. It is located in the nucleoplasm but is not associated with either the nuclear envelope or the nucleolus.
• Species: Human
• Size: 100 ul
• Storage Buffer: 1X Sample Buffer (50 mM Tris-HCl, 2% SDS, 10% glycerol, 300 mM 2-mercaptoethanol, 0.01% Bromophenol blue)
• Applications: Western Blot

Gene Information

• Gene Name: NXF3 nuclear RNA export factor 3 [ Homo sapiens ]
• Official Symbol: NXF3
• Synonyms: NXF3; nuclear RNA export factor 3; TAPL-3; TAP-like protein 3
• Gene ID: 56000
• mRNA Refseq: NM_022052
• Protein Refseq: NP_071335
• MIM: 300316
• UniProt ID: Q9H4D5
• Chromosome Location: Xq22
• Pathway: Herpes simplex infection, organism-specific biosystem; Herpes simplex infection, conserved biosystem; Influenza A, organism-specific biosystem; Influenza A, conserved biosystem; RNA transport, organism-specific biosystem; RNA transport, conserved biosystem; Ribosome biogenesis in eukaryotes, organism-specific biosystem
• Function: mRNA binding; nucleotide binding; protein binding