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Recombinant Human NXN cell lysate

Cat.No. : NXN-1239HCL
  • Specification
  • Gene Information
  • Related Products
Species : Human
Size : 100 ul
Storage Buffer : 1X Sample Buffer (50 mM Tris-HCl, 2% SDS, 10% glycerol, 300 mM 2-mercaptoethanol, 0.01% Bromophenol blue)
Applications : Western Blot;
Gene Name : NXN nucleoredoxin [ Homo sapiens ]
Official Symbol : NXN
Synonyms : NXN; nucleoredoxin; FLJ12614; NRX; nucleoredoxin 1; TRG-4;
Gene ID : 64359
mRNA Refseq : NM_001205319
Protein Refseq : NP_001192248
MIM : 612895
UniProt ID : Q6DKJ4
Chromosome Location : 17p13
Function : oxidoreductase activity; protein-disulfide reductase activity; thioredoxin-disulfide reductase activity;

For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

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Q&As (6)

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What are the applications of NXN in the treatment of oncology? 09/14/2022

The applications of NXN in tumor treatment include: (1) direct killing of tumor cells and inhibition of tumor growth by carrying chemotherapy drugs, siRNAs, etc.; (2) enhanced immunotherapy, which enhances the body's immune response by carrying immunomodulators or vaccines, (3) anti-angiogenic therapy, which inhibits tumor angiogenesis by inhibiting the expression of angiogenesis, and (4) radiotherapy sensitization, which improves the effect of radiotherapy by carrying radioisotopes.

What are the advantages of NXN? 08/10/2021

NXN has the following advantages: (1) high drug loading capacity, which can achieve precise drug delivery, (2) biocompatibility and biodegradability, and no toxic side effects to the body, (3) it can achieve sustained and controlled release of drugs to improve the effect of drug treatment, and (4) it has tumor targeting and cell membrane penetration, which can be used for tumor treatment.

How is NXN prepared? 05/03/2021

The preparation methods of NXN include physicochemical methods and biochemical methods. Among them, the physical and chemical methods include nanoimprint, nanotemplate method, solvent volatilization method and emulsion method, and the biochemical methods include molecular self-assembly, gene coding and cell membrane coating. These methods can be prepared according to the specific application needs.

How do I evaluate the performance of NXN? 09/12/2020

The performance of NXN is mainly evaluated by the following aspects: (1) particle size and morphology analysis, which is characterized by nanoparticle size analyzer, scanning electron microscopy and transmission electron microscopy, (2) drug loading and release performance, which is evaluated by drug content determination and in vitro release experiments, (3) biocompatibility and safety evaluation, cytotoxicity experiments, acute toxicity experiments and immunogenicity evaluation, etc., (4) targeting and in vivo distribution, Fluorescence imaging techniques and other methods to observe.

How about the applications of NXN for other drug delivery? 01/22/2020

In addition to oncology treatment, NXN can also be used in other areas of drug delivery. For example, NXN is used in gene therapy as a carrier for gene drugs such as siRNA and miRNA, NXN is used in antimicrobial therapy as a carrier for antibiotic drugs, and NXN is used in the treatment of neurodegenerative diseases as a carrier for neuroprotective drugs.

How to evaluate the effect of NXN in the treatment of oncology? 12/23/2019

The effect of NXN in tumor treatment is mainly evaluated through the following aspects: (1) tumor growth inhibition effect, observing the growth of tumor after NXN treatment, (2) survival evaluation, observing the survival time of animals after NXN treatment, (3) enhancing immune response effect, detecting the changes of immune indicators of the body after NXN treatment, and (4) safety evaluation, detecting the toxicity and side effects of animals after NXN treatment.

Customer Reviews (3)

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Reviews
06/11/2023

    It has good stability in different environments, with thermal stability, acid and alkali stability.

    10/13/2022

      The storage method is simple, and there is no need to prepare a special environment.

      09/25/2021

        It is highly safe and can be used with confidence.

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