"PADI3" Related Products


Recombinant Human PADI3 cell lysate

Cat.No.: PADI3-1274HCL
Description: This gene encodes a member of the peptidyl arginine deiminase family of enzymes, which catalyze the post-translational deimination of proteins by converting arginine residues into citrullines in the presence of calcium ions. The family members have distinct substrate specificities and tissue-specific expression patterns. The type III enzyme modulates hair structural proteins, such as filaggrin in the hair follicle and trichohyalin in the inner root sheath, during hair follicle formation. Together with the type I enzyme, this enzyme may also play a role in terminal differentiation of the epidermis. This gene exists in a cluster with four other paralogous genes.
Species: Human
Size: 100 ul
Storage Buffer: 1X Sample Buffer (50 mM Tris-HCl, 2% SDS, 10% glycerol, 300 mM 2-mercaptoethanol, 0.01% Bromophenol blue)
Applications: Western Blot;
Gene Name: PADI3 peptidyl arginine deiminase, type III [ Homo sapiens ]
Official Symbol: PADI3
Synonyms: PADI3; peptidyl arginine deiminase, type III; protein-arginine deiminase type-3; PDI3; peptidylarginine deiminase III; protein-arginine deiminase type III; PAD3; MGC126307; MGC126308;
Gene ID: 51702
mRNA Refseq: NM_016233
Protein Refseq: NP_057317
MIM: 606755
UniProt ID: Q9ULW8
Chromosome Location: 1p36.13
Pathway: protein citrullination, organism-specific biosystem; protein citrullination, conserved biosystem;
Function: calcium ion binding; hydrolase activity; protein-arginine deiminase activity;

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