Recombinant Human PCSK4 cell lysate PCSK4-1317HCL

Cat.No.:	PCSK4-1317HCL
Description:	Proprotein convertases, including PCSK4, are calcium-dependent serine proteases related to bacterial subtilisins and to yeast kexin. These enzymes process precursor proteins to their active forms by selective cleavage of the polypeptide at sites following paired basic amino acids. In mammals, this family comprises PC1 (MIM 162150), PC2 (MIM 162151), PC4, PC5 (MIM 600488), furin (FUR; MIM 136950), and PACE4 (MIM 167405). Substrates for these enzymes range from prohormones to precursors for growth factors to cell surface receptors and viral surface glycoproteins (Cao et al., 2001 [PubMed 11776387]).
Species:	Human
Size:	100 ul
Storage Buffer:	1X Sample Buffer (50 mM Tris-HCl, 2% SDS, 10% glycerol, 300 mM 2-mercaptoethanol, 0.01% Bromophenol blue)
Applications:	Western Blot;

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Gene Name:	PCSK4 proprotein convertase subtilisin/kexin type 4 [ Homo sapiens ]
Official Symbol:	PCSK4
Synonyms:	PCSK4; proprotein convertase subtilisin/kexin type 4; DKFZp434B217; MGC34749; PC4; SPC5;
Gene ID:	54760
mRNA Refseq:	NM_017573
Protein Refseq:	NP_060043
MIM:	600487
UniProt ID:	Q6UW60
Chromosome Location:	19p13.3
Function:	peptidase activity; serine-type endopeptidase activity;