Cat.No.:	PYCR1-1448HCL
Description:	This gene encodes an enzyme that catalyzes the NAD(P)H-dependent conversion of pyrroline-5-carboxylate to proline. This enzyme may also play a physiologic role in the generation of NADP(+) in some cell types. The protein forms a homopolymer and localizes to the mitochondrion. Alternate splicing results in two transcript variants encoding different isoforms.
Species:	Human
Size:	100 ul
Storage Buffer:	1X Sample Buffer (50 mM Tris-HCl, 2% SDS, 10% glycerol, 300 mM 2-mercaptoethanol, 0.01% Bromophenol blue)
Applications:	Western Blot;

Gene Name:	PYCR1 pyrroline-5-carboxylate reductase 1 [ Homo sapiens ]
Official Symbol:	PYCR1
Synonyms:	PYCR1; pyrroline-5-carboxylate reductase 1; pyrroline-5-carboxylate reductase 1, mitochondrial; P5C; P5CR 1; P5C reductase 1; proliferation-inducing protein 45; mitochondrial pyrroline-5-carboxylate reductase 1; P5CR; PRO3; PYCR; PIG45; PP222; ARCL2B; ARCL3B;
Gene ID:	5831
mRNA Refseq:	NM_006907
Protein Refseq:	NP_008838
MIM:	179035
UniProt ID:	P32322
Chromosome Location:	17
Pathway:	Amino acid synthesis and interconversion (transamination), organism-specific biosystem; Arginine and proline metabolism, organism-specific biosystem; Arginine and proline metabolism, conserved biosystem; Metabolic pathways, organism-specific biosystem; Metabolism, organism-specific biosystem; Metabolism of amino acids and derivatives, organism-specific biosystem; Proline biosynthesis, glutamate =>
Function:	identical protein binding; nucleotide binding; oxidoreductase activity; oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor; pyrroline-5-carboxylate reductase activity; pyrroline-5-carboxylate reductase activity;

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