Recombinant Human RNF111 cell lysate

• Cat.No.: RNF111-1516HCL

Specification

• Description: The protein encoded by this gene contains a RING finger domain, a motif known to be involved in protein-protein and protein-DNA interactions. The mouse counterpart of this gene (Rnf111/arkadia) has been shown to genetically interact with the transforming growth factor (TGF) beta-like factor Nodal, and act as a modulator of the nodal signaling cascade, which is essential for the induction of mesoderm during embryonic development.
• Species: Human
• Size: 100 ul
• Storage Buffer: 1X Sample Buffer (50 mM Tris-HCl, 2% SDS, 10% glycerol, 300 mM 2-mercaptoethanol, 0.01% Bromophenol blue)
• Applications: Western Blot

Gene Information

• Gene Name: RNF111 ring finger protein 111 [ Homo sapiens ]
• Official Symbol: RNF111
• Synonyms: RNF111; ring finger protein 111; E3 ubiquitin-protein ligase Arkadia; ARK; Arkadia; DKFZP761D081; FLJ38008; DKFZp761D081; DKFZp313E0731; DKFZp686H1966
• Gene ID: 54778
• mRNA Refseq: NM_017610
• Protein Refseq: NP_060080
• MIM: 605840
• UniProt ID: Q6ZNA4
• Chromosome Location: 15q21
• Pathway: Adaptive Immune System, organism-specific biosystem; Antigen processing: Ubiquitination and Proteasome degradation, organism-specific biosystem; Class I MHC mediated antigen processing & presentation, organism-specific biosystem; Immune System, organism-specific biosystem; TGF-beta receptor signaling, organism-specific biosystem
• Function: ligase activity; metal ion binding; protein binding; ubiquitin-protein ligase activity; zinc ion binding