Recombinant Human RNF168 cell lysate

• Cat.No.: RNF168-1520HCL

Specification

• Description: The complex repair response elicited by DNA double-strand breaks (DSBs) includes recruitment of several DNA repair proteins and ubiquitination of H2A-type histones (see MIM 142720). RNF168 is an E3 ubiquitin ligase critical for DSB repair (Stewart et al., 2009 [PubMed 19203578]).
• Species: Human
• Size: 100 ul
• Storage Buffer: 1X Sample Buffer (50 mM Tris-HCl, 2% SDS, 10% glycerol, 300 mM 2-mercaptoethanol, 0.01% Bromophenol blue)
• Applications: Western Blot

Gene Information

• Gene Name: RNF168 ring finger protein 168, E3 ubiquitin protein ligase [ Homo sapiens ]
• Official Symbol: RNF168
• Synonyms: RNF168; ring finger protein 168, E3 ubiquitin protein ligase; ring finger protein 168; E3 ubiquitin-protein ligase RNF168; FLJ35794; FLJ39749
• Gene ID: 165918
• mRNA Refseq: NM_152617
• Protein Refseq: NP_689830
• MIM: 612688
• UniProt ID: Q8IYW5
• Chromosome Location: 3q29
• Function: chromatin binding; histone binding; ligase activity; metal ion binding; protein binding; ubiquitin binding; ubiquitin-protein ligase activity; zinc ion binding