Recombinant Human RNF6 cell lysate RNF6-1529HCL

Recombinant Human RNF6 cell lysate

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Recombinant Human RNF6 cell lysate

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Cat.No. : RNF6-1529HCL
Description : The protein encoded by this gene contains a RING-H2 finger motif. Deletions and mutations in this gene were detected in esophageal squamous cell carcinoma (ESCC), suggesting that this protein may be a potential tumor suppressor. Studies of the mouse counterpart suggested a role of this protein in the transcription regulation that controls germinal differentiation. Multiple alternatively spliced transcript variants encoding the same protein are observed.
Species : Human
Size : 100 ul
Storage Buffer : 1X Sample Buffer (50 mM Tris-HCl, 2% SDS, 10% glycerol, 300 mM 2-mercaptoethanol, 0.01% Bromophenol blue)
Applications : Western Blot;
Gene Name : RNF6 ring finger protein (C3H2C3 type) 6 [ Homo sapiens ]
Official Symbol : RNF6
Synonyms : RNF6; ring finger protein (C3H2C3 type) 6; E3 ubiquitin-protein ligase RNF6; DKFZp686P0776; RING H2 protein RNF 6; RING-H2 protein RNF-6;
Gene ID : 6049
mRNA Refseq : NM_005977
Protein Refseq : NP_005968
MIM : 604242
UniProt ID : Q9Y252
Chromosome Location : 13q12.2
Pathway : Adaptive Immune System, organism-specific biosystem; Antigen processing: Ubiquitination and Proteasome degradation, organism-specific biosystem; Class I MHC mediated antigen processing & presentation, organism-specific biosystem; Immune System, organism-specific biosystem;
Function : DNA binding; androgen receptor binding; ligase activity; metal ion binding; protein binding; ubiquitin-protein ligase activity; zinc ion binding;

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