Recombinant Human RNF6 cell lysate

• Cat.No.: RNF6-1529HCL

Specification

• Description: The protein encoded by this gene contains a RING-H2 finger motif. Deletions and mutations in this gene were detected in esophageal squamous cell carcinoma (ESCC), suggesting that this protein may be a potential tumor suppressor. Studies of the mouse counterpart suggested a role of this protein in the transcription regulation that controls germinal differentiation. Multiple alternatively spliced transcript variants encoding the same protein are observed.
• Species: Human
• Size: 100 ul
• Storage Buffer: 1X Sample Buffer (50 mM Tris-HCl, 2% SDS, 10% glycerol, 300 mM 2-mercaptoethanol, 0.01% Bromophenol blue)
• Applications: Western Blot

Gene Information

• Gene Name: RNF6 ring finger protein (C3H2C3 type) 6 [ Homo sapiens ]
• Official Symbol: RNF6
• Synonyms: RNF6; ring finger protein (C3H2C3 type) 6; E3 ubiquitin-protein ligase RNF6; DKFZp686P0776; RING H2 protein RNF 6; RING-H2 protein RNF-6
• Gene ID: 6049
• mRNA Refseq: NM_005977
• Protein Refseq: NP_005968
• MIM: 604242
• UniProt ID: Q9Y252
• Chromosome Location: 13q12.2
• Pathway: Adaptive Immune System, organism-specific biosystem; Antigen processing: Ubiquitination and Proteasome degradation, organism-specific biosystem; Class I MHC mediated antigen processing & presentation, organism-specific biosystem; Immune System, organism-specific biosystem
• Function: DNA binding; androgen receptor binding; ligase activity; metal ion binding; protein binding; ubiquitin-protein ligase activity; zinc ion binding