Recombinant Human SEC61B cell lysate

• Cat.No.: SEC61B-1578HCL

Specification

• Description: The Sec61 complex is the central component of the protein translocation apparatus of the endoplasmic reticulum (ER) membrane. Oligomers of the Sec61 complex form a transmembrane channel where proteins are translocated across and integrated into the ER membrane. This complex consists of three membrane proteins- alpha, beta, and gamma. This gene encodes the beta-subunit protein. The Sec61 subunits are also observed in the post-ER compartment, suggesting that these proteins can escape the ER and recycle back. There is evidence for multiple polyadenylated sites for this transcript.
• Species: Human
• Size: 100 ul
• Storage Buffer: 1X Sample Buffer (50 mM Tris-HCl, 2% SDS, 10% glycerol, 300 mM 2-mercaptoethanol, 0.01% Bromophenol blue)
• Applications: Western Blot

Gene Information

• Gene Name: SEC61B Sec61 beta subunit [ Homo sapiens ]
• Official Symbol: SEC61B
• Synonyms: SEC61B; Sec61 beta subunit; protein transport protein Sec61 subunit beta; Sec61 complex, beta subunit; protein translocation complex beta; protein transport protein SEC61 beta subunit
• Gene ID: 10952
• mRNA Refseq: NM_006808
• Protein Refseq: NP_006799
• MIM: 609214
• UniProt ID: P60468
• Chromosome Location: 9q22.32-q31.3
• Pathway: Adaptive Immune System, organism-specific biosystem; Antigen processing-Cross presentation, organism-specific biosystem; Class I MHC mediated antigen processing and presentation, organism-specific biosystem; ER-Phagosome pathway, organism-specific biosystem; Gene Expression, organism-specific biosystem; Immune System, organism-specific biosystem
• Function: epidermal growth factor binding; protein binding