Recombinant Human SIGLEC12 cell lysate SIGLEC12-1605HCL

Recombinant Human SIGLEC12 cell lysate


Home / Products / Cell & Tissue Lysates / Recombinant Human SIGLEC12 cell lysate

Recombinant Human SIGLEC12 cell lysate

SIGLEC12 Related Products

Price Inquiry

Welcome! For price inquiries, please feel free to contact us through the form below. We will get back to you as soon as possible.

Cat.No. : SIGLEC12-1605HCL
Description : Sialic acid-binding immunoglobulin-like lectins (SIGLECs) are a family of cell surface proteins belonging to the immunoglobulin superfamily. They mediate protein-carbohydrate interactions by selectively binding to different sialic acid moieties present on glycolipids and glycoproteins. This gene encodes a member of the SIGLEC3-like subfamily of SIGLECs. Members of this subfamily are characterized by an extracellular V-set immunoglobulin-like domain followed by two C2-set immunoglobulin-like domains, and the cytoplasmic tyrosine-based motifs ITIM and SLAM-like. The encoded protein, upon tyrosine phosphorylation, has been shown to recruit the Src homology 2 domain-containing protein-tyrosine phosphatases SHP1 and SHP2. It has been suggested that the protein is involved in the negative regulation of macrophage signaling by functioning as an inhibitory receptor. This gene is located in a cluster with other SIGLEC3-like genes on 19q13.4. Alternatively spliced transcript variants encoding distinct isoforms have been described for this gene.
Species : Human
Size : 100 ul
Storage Buffer : 1X Sample Buffer (50 mM Tris-HCl, 2% SDS, 10% glycerol, 300 mM 2-mercaptoethanol, 0.01% Bromophenol blue)
Applications : Western Blot;
Gene Name : SIGLEC12 sialic acid binding Ig-like lectin 12 (gene/pseudogene) [ Homo sapiens ]
Official Symbol : SIGLEC12
Synonyms : SIGLEC12; sialic acid binding Ig-like lectin 12 (gene/pseudogene); sialic acid binding Ig like lectin 12 , SIGLEC like 1 , SIGLECL1; sialic acid-binding Ig-like lectin 12; S2V; Siglec 12; Siglec L1; Siglec XII; SLG; SIGLEC-like 1; sialic acid-binding Ig-like lectin-like 1; SIGLECL1; Siglec-XII; FLJ38600;
Gene ID : 89858
mRNA Refseq : NM_033329
Protein Refseq : NP_201586
MIM : 606094
UniProt ID : Q96PQ1
Chromosome Location : 19q13.41
Function : sugar binding;

Online Inquiry

  • Note: There will be extra charge for optional service!
  • Please input "biomart" as verification code. Please review Creative BioMart's privacy policy for more information

Optional Service: Optional requirements on this protein

Other Requirements:

Apply For A Coupon

$50 OFF Your First Purchase

Apply For a Coupon

Enter your email here to subscribe.

creative biomart inc.

Easy access to products and services you need from our library via powerful searching tools.

Follow Us

Copyright © 2007 – 2020 Creative BioMart. All Rights Reserved. Terms and Conditions | Privacy Policy