Recombinant Human SMC3 cell lysate

• Cat.No.: SMC3-1648HCL

Specification

• Description: This gene belongs to the SMC3 subfamily of SMC proteins. The encoded protein occurs in certain cell types as either an intracellular, nuclear protein or a secreted protein. The nuclear form, known as structural maintenance of chromosomes 3, is a component of the multimeric cohesin complex that holds together sister chromatids during mitosis, enabling proper chromosome segregation. Post-translational modification of the encoded protein by the addition of chondroitin sulfate chains gives rise to the secreted proteoglycan bamacan, an abundant basement membrane protein.
• Species: Human
• Size: 100 ul
• Storage Buffer: 1X Sample Buffer (50 mM Tris-HCl, 2% SDS, 10% glycerol, 300 mM 2-mercaptoethanol, 0.01% Bromophenol blue)
• Applications: Western Blot

Gene Information

• Gene Name: SMC3 structural maintenance of chromosomes 3 [ Homo sapiens ]
• Official Symbol: SMC3
• Synonyms: SMC3; structural maintenance of chromosomes 3; chondroitin sulfate proteoglycan 6 (bamacan) , CSPG6; structural maintenance of chromosomes protein 3; BAM; bamacan; bamacan proteoglycan; HCAP; SMC3L1; SMC-3; SMC protein 3; chromosome-associated polypeptide; chondroitin sulfate proteoglycan 6 (bamacan); basement membrane-associated chondroitin proteoglycan; BMH; CDLS3; CSPG6
• Gene ID: 9126
• mRNA Refseq: NM_005445
• Protein Refseq: NP_005436
• MIM: 606062
• UniProt ID: Q9UQE7
• Chromosome Location: 10q25
• Pathway: Cell Cycle, organism-specific biosystem; Cell Cycle, Mitotic, organism-specific biosystem; Cell cycle, organism-specific biosystem; Cell cycle, conserved biosystem; Chromosome Maintenance, organism-specific biosystem; DNA Replication, organism-specific biosystem; M Phase, organism-specific biosystem
• Function: ATP binding; dynein binding; microtubule motor activity; nucleotide binding; protein binding; protein heterodimerization activity