Recombinant Human STX1A cell lysate

• Cat.No.: STX1A-1717HCL

Specification

• Description: Synaptic vesicles store neurotransmitters that are released during calcium-regulated exocytosis. The specificity of neurotransmitter release requires the localization of both synaptic vesicles and calcium channels to the presynaptic active zone. Syntaxins function in this vesicle fusion process. Syntaxins also serve as a substrate for botulinum neurotoxin type C, a metalloprotease that blocks exocytosis and has high affinity for a molecular complex that includes the alpha-latrotoxin receptor (MIM 600565) which produces explosive exocytosis (Zhang et al., 1995 [PubMed 7622072]).
• Species: Human
• Size: 100 ul
• Storage Buffer: 1X Sample Buffer (50 mM Tris-HCl, 2% SDS, 10% glycerol, 300 mM 2-mercaptoethanol, 0.01% Bromophenol blue)
• Applications: Western Blot

Gene Information

• Gene Name: STX1A syntaxin 1A (brain) [ Homo sapiens ]
• Official Symbol: STX1A
• Synonyms: STX1A; syntaxin 1A (brain); STX1; syntaxin-1A; HPC 1; p35 1; neuron-specific antigen HPC-1; HPC-1; P35-1; SYN1A
• Gene ID: 6804
• mRNA Refseq: NM_001165903
• Protein Refseq: NP_001159375
• MIM: 186590
• UniProt ID: Q16623
• Chromosome Location: 7q11.2
• Pathway: Acetylcholine Neurotransmitter Release Cycle, organism-specific biosystem; Amphetamine addiction, organism-specific biosystem; Amphetamine addiction, conserved biosystem; Botulinum neurotoxicity, organism-specific biosystem; Diabetes pathways, organism-specific biosystem; Disease, organism-specific biosystem; Dopamine Neurotransmitter Release Cycle, organism-specific biosystem
• Function: ATP-dependent protein binding; SNAP receptor activity; SNARE binding; calcium channel inhibitor activity; calcium-dependent protein binding; glycoprotein binding; myosin binding; myosin head/neck binding; protein N-terminus binding; protein binding; protein binding, bridging; protein domain specific binding; protein heterodimerization activity