"TFAM" Related Products


Recombinant Human TFAM cell lysate

Cat.No.: TFAM-1765HCL
Description: This gene encodes a mitochondrial transcription factor that is a key activator of mitochondrial transcription as well as a participant in mitochondrial genome replication. Studies in mice have demonstrated that this gene product is required to regulate the mitochondrial genome copy number and is essential for embryonic development. A mouse model for Kearns-Sayre syndrome was produced when expression of this gene was eliminated by targeted disruption in heart and muscle cells.
Species: Human
Size: 100 ul
Storage Buffer: 1X Sample Buffer (50 mM Tris-HCl, 2% SDS, 10% glycerol, 300 mM 2-mercaptoethanol, 0.01% Bromophenol blue)
Applications: Western Blot;
Gene Name: TFAM transcription factor A, mitochondrial [ Homo sapiens ]
Official Symbol: TFAM
Synonyms: TFAM; transcription factor A, mitochondrial; TCF6, TCF6L2; TCF-6; transcription factor 6; mitochondrial transcription factor 1; mitochondrial transcription factor A; Transcription factor 6-like 2 (mitochondrial transcription factor); TCF6; MtTF1; mtTFA; TCF6L1; TCF6L2; TCF6L3;
Gene ID: 7019
mRNA Refseq: NM_003201
Protein Refseq: NP_003192
MIM: 600438
UniProt ID: Q00059
Chromosome Location: 10q21
Pathway: Energy Metabolism, organism-specific biosystem; Gene Expression, organism-specific biosystem; Huntingtons disease, organism-specific biosystem; Huntingtons disease, conserved biosystem; Mitochondrial Gene Expression, organism-specific biosystem; Mitochondrial transcription initiation, organism-specific biosystem; RNA Polymerase I, RNA Polymerase III, and Mitochondrial Transcription, organism-specific biosystem;
Function: DNA binding; chromatin binding; mitochondrial light strand promoter sense binding; protein binding; sequence-specific DNA binding transcription factor activity;

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