Recombinant Human TH1L cell lysate

• Cat.No.: TH1L-1769HCL

Specification

• Description: The NELF complex of proteins interacts with the DSIF protein complex to repress transcriptional elongation by RNA polymerase II. The protein encoded by this gene is an essential part of the NELF complex. Alternative translation initiation site usage results in the formation of two isoforms with different N-termini.
• Species: Human
• Size: 100 ul
• Storage Buffer: 1X Sample Buffer (50 mM Tris-HCl, 2% SDS, 10% glycerol, 300 mM 2-mercaptoethanol, 0.01% Bromophenol blue)
• Applications: Western Blot

Gene Information

• Gene Name: TH1L TH1-like (Drosophila) [ Homo sapiens ]
• Official Symbol: TH1L
• Synonyms: TH1L; TH1-like (Drosophila); TH1 like (Drosophila homolog); negative elongation factor C/D; HSPC130; NELF C; NELF D; TH1; trihydrophobin 1; NELF-C/D; TH1-like protein; TH1 drosophila homolog; negative elongation factor proteins C and D; NELF-C; NELF-D
• Gene ID: 51497
• mRNA Refseq: NM_198976
• Protein Refseq: NP_945327
• MIM: 605297
• UniProt ID: Q8IXH7
• Chromosome Location: 20q13
• Pathway: Abortive elongation of HIV-1 transcript in the absence of Tat, organism-specific biosystem; Disease, organism-specific biosystem; Formation of HIV-1 elongation complex containing HIV-1 Tat, organism-specific biosystem; Formation of HIV-1 elongation complex in the absence of HIV-1 Tat, organism-specific biosystem; Formation of RNA Pol II elongation complex, organism-specific biosystem; Formation of the Early Elongation Complex, organism-specific biosystem; Formation of the HIV-1 Early Elongation Complex, organism-specific biosystem
• Function: protein binding