Recombinant Human THEM4 cell lysate

• Cat.No.: THEM4-1775HCL

Specification

• Description: Protein kinase B (PKB) is a major downstream target of receptor tyrosine kinases that signal via phosphatidylinositol 3-kinase. Upon cell stimulation, PKB is translocated to the plasma membrane, where it is phosphorylated in the C-terminal regulatory domain. The protein encoded by this gene negatively regulates PKB activity by inhibiting phosphorylation. Transcription of this gene is commonly downregulated in glioblastomas.
• Species: Human
• Size: 100 ul
• Storage Buffer: 1X Sample Buffer (50 mM Tris-HCl, 2% SDS, 10% glycerol, 300 mM 2-mercaptoethanol, 0.01% Bromophenol blue)
• Applications: Western Blot

Gene Information

• Gene Name: THEM4 thioesterase superfamily member 4 [ Homo sapiens ]
• Official Symbol: THEM4
• Synonyms: THEM4; thioesterase superfamily member 4; C terminal modulator protein; CTMP; C-terminal modulator protein; carboxyl-terminal modulator protein; FLJ27206; MGC29636
• Gene ID: 117145
• mRNA Refseq: NM_053055
• Protein Refseq: NP_444283
• MIM: 606388
• UniProt ID: Q5T1C6
• Chromosome Location: 1q21.3
• Pathway: Activation of PKB, organism-specific biosystem; Adaptive Immune System, organism-specific biosystem; CD28 co-stimulation, organism-specific biosystem; CD28 dependent PI3K/Akt signaling, organism-specific biosystem; Costimulation by the CD28 family, organism-specific biosystem; Disease, organism-specific biosystem; Downstream Signaling Events Of B Cell Receptor (BCR), organism-specific biosystem