Recombinant Human TRIM28 cell lysate

• Cat.No.: TRIM28-1825HCL

Specification

• Description: The protein encoded by this gene mediates transcriptional control by interaction with the Kruppel-associated box repression domain found in many transcription factors. The protein localizes to the nucleus and is thought to associate with specific chromatin regions. The protein is a member of the tripartite motif family. This tripartite motif includes three zinc-binding domains, a RING, a B-box type 1 and a B-box type 2, and a coiled-coil region.
• Species: Human
• Size: 100 ul
• Storage Buffer: 1X Sample Buffer (50 mM Tris-HCl, 2% SDS, 10% glycerol, 300 mM 2-mercaptoethanol, 0.01% Bromophenol blue)
• Applications: Western Blot

Gene Information

• Gene Name: TRIM28 tripartite motif containing 28 [ Homo sapiens ]
• Official Symbol: TRIM28
• Synonyms: TRIM28; tripartite motif containing 28; transcription intermediary factor 1-beta; KAP1; RNF96; TF1B; TIF1B; KAP-1; KRIP-1; TIF1-beta; RING finger protein 96; KRAB-associated protein 1; nuclear corepressor KAP-1; KRAB-interacting protein 1; E3 SUMO-protein ligase TRIM28; tripartite motif-containing 28; tripartite motif-containing protein 28; transcriptional intermediary factor 1-beta; FLJ29029
• Gene ID: 10155
• mRNA Refseq: NM_005762
• Protein Refseq: NP_005753
• MIM: 601742
• UniProt ID: Q13263
• Chromosome Location: 19q13.4
• Pathway: C-MYB transcription factor network, organism-specific biosystem; E2F transcription factor network, organism-specific biosystem; Gene Expression, organism-specific biosystem; Generic Transcription Pathway, organism-specific biosystem; p53 pathway, organism-specific biosystem
• Function: DNA binding; chromo shadow domain binding; ligase activity; metal ion binding; protein binding; protein kinase activity; contributes_to sequence-specific DNA binding; contributes_to sequence-specific DNA binding transcription factor activity; transcription coactivator activity; transcription corepressor activity; ubiquitin protein ligase binding; ubiquitin-protein ligase activity; zinc ion binding