Recombinant Human ZNRF1 cell lysate

• Cat.No.: ZNRF1-2097HCL

Specification

• Description: In a study identifying genes in rat that are upregulated in response to nerve damage, a gene which is highly expressed in ganglia and in the central nervous system was found. The protein encoded by the rat gene contains both a zinc finger and a RING finger motif and is localized in the endosome/lysosome compartment, indicating that it may be involved in ubiquitin-mediated protein modification. The protein encoded by this human gene is highly similar in sequence to that encoded by the rat gene.
• Species: Human
• Size: 100 ul
• Storage Buffer: 1X Sample Buffer (50 mM Tris-HCl, 2% SDS, 10% glycerol, 300 mM 2-mercaptoethanol, 0.01% Bromophenol blue)
• Applications: Western Blot

Gene Information

• Gene Name: ZNRF1 zinc and ring finger 1, E3 ubiquitin protein ligase [ Homo sapiens ]
• Official Symbol: ZNRF1
• Synonyms: ZNRF1; zinc and ring finger 1, E3 ubiquitin protein ligase; zinc and ring finger 1; E3 ubiquitin-protein ligase ZNRF1; DKFZp434E229; FLJ14846; nin283; nerve injury gene 283; zinc/RING finger protein 1; zinc and ring finger protein 1; nerve injury-induced gene 283 protein; NIN283; FLJ46491; MGC15430
• Gene ID: 84937
• mRNA Refseq: NM_032268
• Protein Refseq: NP_115644
• MIM: 612060
• UniProt ID: Q8ND25
• Chromosome Location: 16q22.3
• Function: ligase activity; metal ion binding; protein binding; ubiquitin-protein ligase activity; zinc ion binding