"AAK1" Related Products

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Recombinant Human AAK1 cell lysate

Cat.No.: AAK1-2106HCL
Description: Adaptor-related protein complex 2 (AP-2 complexes) functions during receptor-mediated endocytosis to trigger clathrin assembly, interact with membrane-bound receptors, and recruit encodytic accessory factors. This gene encodes a member of the SNF1 subfamily of Ser/Thr protein kinases. The protein interacts with and phosphorylates a subunit of the AP-2 complex, which promotes binding of AP-2 to sorting signals found in membrane-bound receptors and subsequent receptor endocytosis. Its kinase activity is stimulated by clathrin. Alternatively spliced transcript variants have been described, but their biological validity has not been determined.
Species: Human
Size: 100 ul
Storage Buffer: 1X Sample Buffer (50 mM Tris-HCl, 2% SDS, 10% glycerol, 300 mM 2-mercaptoethanol, 0.01% Bromophenol blue)
Applications: Western Blot;
Gene Name: AAK1 AP2 associated kinase 1 [ Homo sapiens ]
Official Symbol: AAK1
Synonyms: AAK1; AP2 associated kinase 1; AP2-associated protein kinase 1; DKFZp686K16132; KIAA1048; adaptor-associated kinase 1; FLJ23712; FLJ25931; FLJ31060; FLJ42882; FLJ45252; MGC138170; MGC164568; MGC164570; DKFZp686F03202;
Gene ID: 22848
mRNA Refseq: NM_014911
Protein Refseq: NP_055726
UniProt ID: Q2M2I8
Chromosome Location: 2p24.3-p14
Function: AP-2 adaptor complex binding; ATP binding; Notch binding; nucleotide binding; protein serine/threonine kinase activity;

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