Active Recombinant Human GALNS, HIS-tagged
Cat.No. : | GALNS-111H |
Product Overview : | Human GALNS recombinant protein, Ala27-His522, with an N-terminal 6-His tag, was expressed in baculovirus expression system. |
- Specification
- Gene Information
- Related Products
Description : | This gene encodes N-acetylgalactosamine-6-sulfatase which is a lysosomal exohydrolase required for the degradation of the glycosaminoglycans, keratan sulfate, and chondroitin 6-sulfate. Sequence alterations including point, missense and nonsense mutations, as well as those that affect splicing, result in a deficiency of this enzyme. Deficiencies of this enzyme lead to Morquio A syndrome, a lysosomal storage disorder. |
Source : | Sf 21 |
Species : | Human |
Tag : | His |
Predicted N Terminal : | His & Thr56 |
Form : | Supplied as a 0.2 µm filtered solution in Tris and NaCl. See Certificate of Analysis for details. |
Bio-activity : | Measured by its ability to hydrolyze the substrate 4-Nitrocatechol Sulfate (PNCS). |
Molecular Mass : | Predicted Molecular Mass:56 kDaSDS-PAGE:53-59 kDa, reducing conditions |
Endotoxin : | < 1.0 EU per 1 μg of the protein by the LAL method. |
Purity : | >90%, by SDS-PAGE under reducing conditions and visualized by Colloidal Coomassie® Blue stain at 5 µg per lane. |
Storage : | Avoid repeated freeze-thaw cycles.6 months from date of receipt, -20 to -70 °C as supplied.3 months, -20 to -70 °C under sterile conditions after opening. |
Gene Name : | GALNS galactosamine (N-acetyl)-6-sulfatase [ Homo sapiens (human) ] |
Official Symbol : | GALNS |
Synonyms : | GAS; MPS4A; GalN6S; GALNAC6S; N-acetylgalactosamine-6-sulfatase; chondroitinase; galNAc6S sulfatase; chondroitinsulfatase; galactose-6-sulfate sulfatase; N-acetylgalactosamine-6-sulfate sulfatase; galactosamine (N-acetyl)-6-sulfate sulfatase |
Gene ID : | 2588 |
mRNA Refseq : | NM_000512 |
Protein Refseq : | NP_000503 |
MIM : | 612222 |
UniProt ID : | P34059 |
Chromosome Location : | 16q24.3 |
Pathway : | Chondroitin sulfate degradation, organism-specific biosystem; Chondroitin sulfate degradation, conserved biosystem; Glycosaminoglycan degradation, conserved biosystem |
Function : | N-acetylgalactosamine-4-sulfatase activity; N-acetylgalactosamine-6-sulfatase activity; sulfuric ester hydrolase activity |
Products Types
◆ Recombinant Protein | ||
GALNS-0129H | Recombinant Human GALNS Protein (M1-H522), His tagged | +Inquiry |
GALNS-0128H | Recombinant Human GALNS Protein (M1-H522), Tag Free | +Inquiry |
GALNS-2120R | Recombinant Rat GALNS Protein, His (Fc)-Avi-tagged | +Inquiry |
GALNS-515H | Recombinant Human GALNS Protein (27-522 aa), GST-tagged | +Inquiry |
GALNS-1398H | Recombinant Human GALNS Protein (27-522 aa), His-tagged | +Inquiry |
◆ Lysates | ||
GALNS-6040HCL | Recombinant Human GALNS 293 Cell Lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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