Active Recombinant Human PLK3, GST-tagged

• Cat.No.: PLK3-1069H
• Product Overview: Recombinant human PLK3 (57-340) was expressed by baculovirus in Sf9 insect cells using an N-terminal GST tag.

Specification

• Description: Cytokine-inducible kinase is a putative serine/threonine kinase. CNK contains both a catalytic domain and a putative regulatory domain. It may play a role in regulation of cell cycle progression and tumorigenesis.?
• Source: Sf9 insect cells
• Species: Human
• Tag: GST
• Form: Recombinant protein stored in 50mM Tris-HCl, pH 7.5, 150mM NaCl, 10mM glutathione, 0.1mM EDTA, 0.25mM DTT, 0.1mM PMSF, 25% glycerol.
• Bio-activity: 2.2 nmol/min/mg
• Molecular Mass: ~60 kDa
• Protein length: 57-340
• Purity: >75%
• Applications: Kinase Assay; Western Blot
• Stability: 1 yr at -70oC from date of shipment.
• Storage: Store product at –70oC. For optimal storage, aliquot target into smaller quantities after centrifugation and store at recommended temperature. For most favorable performance, avoid repeated handling and multiple freeze/thaw cycles.
• Concentration: 0.1 ug/ul

Gene Information

• Gene Name: PLK3?polo-like kinase 3 [?Homo sapiens?(human) ]
• Official Symbol: PLK3
• Synonyms: polo-like kinase 3 (Drosophila); CNK; FNK; PRK; PLK3; serine/threonine-protein kinase PLK3; PLK-3; FGF-inducible kinase; cytokine-inducible kinase; proliferation-related kinase; cytokine-inducible serine/threonine-protein kinase;?Polo-like kinase 3; Proliferation-related kinase; Cytokine-inducible serine/threonine-protein kinase; EC 2.7.11.21
• Gene ID: 1263
• mRNA Refseq: NM_004073
• Protein Refseq: NP_004064
• MIM: 602913
• UniProt ID: Q9H4B4
• Chromosome Location: 1p34.1
• Pathway: Direct p53 effectors; FoxO signaling pathway; PLK3 signaling events
• Function: ATP binding; p53 binding; protein binding; protein serine/threonine kinase activity