"ADA" Related Products


Recombinant Human Adenosine Deaminase

Cat.No.: ADA-3H
Description: ADA, also known as adenosine deaminase, catalyzes the hydrolytic deamination of adenosine and 2-deoxyadenosine. This protein plays an important role in purine metabolism and in adenosine homeostasis. ADA acts as a positive regulator of T-cell coactivation, by binding DPP4. Its interaction with DPP4 regulates lymphocyte-epithelial cell adhesion.
Species: Human
Form: Liquid
Endotoxin: < 1.0 EU per μg of the protein as determined by the LAL method
Purity: Greater than 90% as determined by Analysis by SDS-PAGE.
Usage: For Research Use Only! Not For Use in Humans.
Storage: Store at -20 °C, for extended storage, conserve at -20 °C or -80 °C. Repeated freezing and thawing is not recommended. Store working aliquots at 4 °C for up to one week.
Storage Buffer: Tris-based buffer,50% glycerol
Gene Name: ADA adenosine deaminase [ Homo sapiens ]
Official Symbol: ADA
Synonyms: ADA; adenosine deaminase; adenosine aminohydrolase;
Gene ID: 100
mRNA Refseq: NM_000022
Protein Refseq: NP_000013
MIM: 608958
UniProt ID: P00813
Chromosome Location: 20q13.12
Pathway: C-MYB transcription factor network, organism-specific biosystem; Metabolic pathways, organism-specific biosystem; Metabolism, organism-specific biosystem; Metabolism of nucleotides, organism-specific biosystem; Primary immunodeficiency, organism-specific biosystem; Primary immunodeficiency, conserved biosystem; Purine metabolism, organism-specific biosystem;
Function: adenosine deaminase activity; adenosine deaminase activity; hydrolase activity; metal ion binding; protein binding; purine nucleoside binding; zinc ion binding; zinc ion binding;

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Optional requirements on this protein    +Expand
C-fusion    N-fusion   Non-tagged
His    GST   Fc   Others
<1.0 eu/μg    <0.1 eu/μg   <0.01 eu/μg   Not required
Monomer Isolation    Dimer Isolation    Not required
>80% by SDS-PAGE    >90% by SDS-PAGE   >95% by SDS-PAGE   Others

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