Native Apis mellifera Phospholipase A2

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Native Apis mellifera Phospholipase A2

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Cat.No. : Pla2-85A
Product Overview : Native Apis mellifera Phospholipase A2 was purified from honey bee venom.
Description : Phospholipases A2 (PLA2s) EC 3.1.1.4 are enzymes that release fatty acids from the second carbon group of glycerol. This particular phospholipase specifically recognizes the sn-2 acyl bond of phospholipids and catalytically hydrolyzes the bond releasing arachidonic acid and lysophospholipids. Upon downstream modification by cyclooxygenases, arachidonic acid is modified into active compounds called eicosanoids. Eicosanoids include prostaglandins and leukotrienes, which are categorized as anti-inflammatory and inflammatory mediators.
Source : Honey bee venom
Species : Honey bee
Form : salt-free, lyophilized powder
Bio-activity : 600-2400 units/mg protein
Unit Definition : One unit will hydrolyze 1.0 μmole of soybean L-α-phosphatidylcholine to L-α-lysophosphatidylcholine and a fatty acid per min at pH 8.9 at 25 °C.
Storage : Store at -20 °C
Gene Name : Pla2 phospholipase A2 [ Apis mellifera ]
Official Symbol : Pla2
Synonyms : bvPLA2; GB13351; phospholipase A2; allergen Api m 1; allergen Api m Iphosphatidyl; choline 2-acylhydrolase
Gene ID : 406141
mRNA Refseq : NM_001011614
Protein Refseq : NP_001011614
UniProt ID : P00630
Chromosome Location : chromosome: LG13

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