"KIR2DL3" Related Products

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Recombinant Human KIR2DL3, Fc-tagged

Cat.No.: KIR2DL3-164H
Product Overview: Recombinant Human KIR2DL3 /CD158B2 Protein,C-Fc Tag (rh KIR2DL3 / CD158B2 Fc Chimera) His 22 - His 245 (Accession # NP_056952) was produced in human 293 cells (HEK293).
Description: Killer cell immunoglobulin-like receptor 2DL3 (KIR2DL3) is also known as CD158 antigen-like family member B2, KIR-023GB, Killer inhibitory receptor cl 2-3, MHC class I NK cell receptor, NKAT2a, NKAT2b, Natural killer-associated transcript 2, p58 natural killer cell receptor clone CL-6, p58.2 MHC class-I-specific NK receptor, CD158b2 and KIR2DL3, which is a single-pass type I membrane protein and belongs to the immunoglobulin superfamily.KIR2DL3 is a receptor on natural killer (NK) cells for HLA-C alleles (HLA-Cw1, HLA-Cw3 and HLA-Cw7). KIR2DL3 can inhibit the activity of NK cells thus preventing cell lysis.
Source: HEK293
Species: Human
Tag: Fc
Predicted N Terminal: His 22
Form: Lyophilized from 0.22 μm filtered solution in 50 mM tris, 100 mM glycine, pH7.5. Normally Mannitol or Trehalose are added as protectants before lyophilization.
Molecular Mass: rh KIR2DL3 / CD158B2 Fc Chimera is fused with a human IgG1 Fc tag at the C-terminus, and has a calculated MW of 51.2 kDa. The predicted N-terminus is His 22. DTT-reduced Protein migrates as 66-80 kDa in SDS-PAGE due to glycosylation.
Endotoxin: Less than 1.0 EU per μg of the rh KIR2DL3 / CD158B2 Fc Chimera by the LAL method.
Purity: >95% as determined by SDS-PAGE.
Applications: CD Antigens
Storage: Avoid repeated freeze-thaw cycles.No activity loss was observed after storage at:In lyophilized state for 1 year (4oC); After reconstitution under sterile conditions for 3 months (-70oC).
Gene Name: KIR2DL3 killer cell immunoglobulin-like receptor, two domains, long cytoplasmic tail, 3 [ Homo sapiens ]
Official Symbol: KIR2DL3
Synonyms: KIR2DL3; killer cell immunoglobulin-like receptor, two domains, long cytoplasmic tail, 3; killer cell immunoglobulin-like receptor 2DL3; CD158B2; cl 6; nkat2; nkat2a; nkat2b; p58; NKAT-2; NK-receptor; p58 NK receptor CL-6; MHC class I NK cell receptor; killer inhibitory receptor cl 2-3; CD158 antigen-like family member B2; natural killer associated transcript 2; natural killer-associated transcript 2; p58.2 MHC class-I specific NK receptor; p58.2 MHC class-I-specific NK receptor; p58 natural killer cell receptor clone CL-6; natural killer cell inhibitory receptor KIR2DL3; NKAT; GL183; NKAT2; CD158b; NKAT2A; NKAT2B; KIR-K7b; KIR-K7c; KIRCL23; KIR-023GB; MGC129943;
Gene ID: 3804
mRNA Refseq: NM_015868
Protein Refseq: NP_056952
MIM: 604938
UniProt ID: P43628
Chromosome Location: 19q13.4
Pathway: Adaptive Immune System, organism-specific biosystem; Antigen processing and presentation, organism-specific biosystem; Antigen processing and presentation, conserved biosystem; Graft-versus-host disease, organism-specific biosystem; Graft-versus-host disease, conserved biosystem; Immune System, organism-specific biosystem; Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell, organism-specific biosystem;
Function: antigen binding; protein binding; receptor activity;

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