Recombinant Human KDM3B, FLAG-tagged


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Recombinant Human KDM3B, FLAG-tagged

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Cat.No. : KDM3B-49H
Product Overview : Recombinant Human KDM3B (accession number NP_057688.2) was expressed in Sf9 cells and contains an N-terminal FLAG tag with a molecular weight of 193.4 kDa.
Description : Lysine (K)-specific demethylase 3B (KDM3B), also known as Jumonji domain-containing protein 1B (JMJD1B), is a histone demethylase that specifically demethylates lysine 9 of histone H3 (H3K9), thereby playing a central role in defining the histone code. Demethylation of lysine residues generates formaldehyde and succinate. KDM3B may have tumor suppressor activity.
Source : Sf9 insect cells
Species : Human
Tag : FLAG
Form : 40 mM HEPES pH 7.4, 150 mM NaCl and 20% glycerol.
Bio-activity : H3K9me2 demethylase.
Applications : Enzyme kinetics, inhibitor screening, and selectivity profiling.
Storage : Recombinant proteins in solution are temperature sensitive and must be stored at -80°C to prevent degradation. Avoid repeated freeze/thaw cycles and keep on ice when not in storage.
Concentration : 0.9 mg/ml
Gene Name : KDM3B lysine (K)-specific demethylase 3B [ Homo sapiens ]
Official Symbol : KDM3B
Synonyms : KDM3B; lysine (K)-specific demethylase 3B; C5orf7, chromosome 5 open reading frame 7 , JMJD1B, jumonji domain containing 1B; lysine-specific demethylase 3B; KIAA1082; NET22; nuclear protein 5qNCA; jumonji domain containing 1B; jumonji domain-containing protein 1B; jmjC domain-containing histone demethylation protein 2B; 5qNCA; C5orf7; JMJD1B;
Gene ID : 51780
mRNA Refseq : NM_016604
Protein Refseq : NP_057688
MIM : 609373
UniProt ID : Q7LBC6
Chromosome Location : 5q31
Function : metal ion binding; oxidoreductase activity; oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen;
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

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