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Recombinant Human SMYD1, FLAG-tagged

Cat.No.: Smyd1-73H
Product Overview: Recombinant Human Smyd1 (accession number NP_938015.1) was expressed in Sf9 cells and contains an N-terminal FLAG tag with an observed molecular weight of 58.3 kDa.
Description: SET and MYND domain-containing protein 1 (Smyd1) is a member of the Smyd family of histone methyltransferases that possesses H3K4 methyltransferase activity. It has also been shown to act as a transcriptional repressor. Studies suggest that Smyd1 may play a critical role in cardiomyocyte differentiation and cardiac morphogenesis and that it also may have a function in skeletal muscle development.
Source: Sf9 insect cells
Species: Human
Tag: FLAG
Form: 20 mM Tris-HCl pH 7.4, 150 mM NaCl and 20% glycerol.
Bio-activity: Not known. May methylate non-histone substrates.
Applications: Enzyme kinetics, inhibitor screening, and selectivity profiling.
Storage: Recombinant proteins in solution are temperature sensitive and must be stored at -80°C to prevent degradation. Avoid repeated freeze/thaw cycles and keep on ice when not in storage.
Concentration: 0.4 mg/ml
Gene Name: SMYD1 SET and MYND domain containing 1 [ Homo sapiens ]
Official Symbol: Smyd1
Synonyms: SMYD1; SET and MYND domain containing 1; SET and MYND domain-containing protein 1; BOP; KMT3D; ZMYND22; CD8 beta opposite; zinc finger, MYND domain containing 18; ZMYND18;
Gene ID: 150572
mRNA Refseq: NM_198274
Protein Refseq: NP_938015
MIM: 606846
UniProt ID: Q8NB12
Chromosome Location: 2p11.1
Pathway: Heart Development, organism-specific biosystem;
Function: DNA binding; metal ion binding; transcription corepressor activity; zinc ion binding;

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