Recombinant Human BCL10 Protein, His-tagged
Cat.No. : | BCL10-16H |
Product Overview : | Recombinant human BCL10 protein (1-233aa), fused to His-tag at N-terminus, was expressed in E. coli and purified by using conventional chromatography. |
- Specification
- Gene Information
- Related Products
Description : | This gene was identified by its translocation in a case of mucosa-associated lymphoid tissue (MALT) lymphoma. The protein encoded by this gene contains a caspase recruitment domain (CARD), and has been shown to induce apoptosis and to activate NF-kappaB. This protein is reported to interact with other CARD domain containing proteins including CARD9, 10, 11 and 14, which are thought to function as upstream regulators in NF-kappaB signaling. This protein is found to form a complex with MALT1, a protein encoded by another gene known to be translocated in MALT lymphoma. MALT1 and this protein are thought to synergize in the activation of NF-kappaB, and the deregulation of either of them may contribute to the same pathogenetic process that leads to the malignancy. Alternative splicing results in multiple transcript variants. |
Source : | E. coli |
Species : | Human |
Tag : | His |
Form : | Liquid |
Molecular Mass : | 28.8 kDa (257aa) |
AA Sequence : | MGSSHHHHHHSSGLVPRGSHMGSHM EPTAPSLTEEDLTEVKKDALENLRV YLCEKIIAERHFDHLRAKKILSRED TEEISCRTSSRKRAGKLLDYLQENP KGLDTLVESIRREKTQNFLIQKITD EVLKLRNIKLEHLKGLKCSSCEPFP DGATNNLSRSNSDESNFSEKLRAST VMYHPEGESSTTPFFSTNSSLNLPV LEVGRTENTIFSSTTLPRPGDPGAP PLPPDLQLEEEGTCANSSEMFLPLR SRTVSRQ |
Purity : | > 85% by SDS-PAGE |
Applications : | SDS-PAGE |
Storage : | Can be stored at 2 to 8 centigrade for 1 week. For long term storage, aliquot and store at -20 to -80 centigrade. Avoid repeated freezing and thawing cycles. |
Concentration : | 0.5 mg/mL (determined by Bradford assay) |
Storage Buffer : | 20mM Tris-HCl buffer (pH 8.0) containing 10% glycerol, 0.05M NaCl, 1mM DTT |
Gene Name : | BCL10 BCL10 immune signaling adaptor [ Homo sapiens (human) ] |
Official Symbol : | BCL10 |
Synonyms : | BCL10; BCL10 immune signaling adaptor; CLAP; mE10; CIPER; IMD37; c-E10; CARMEN; B-cell lymphoma/leukemia 10; B cell CLL/lymphoma 10; CARD containing molecule enhancing NF-kB; CARD-containing apoptotic signaling protein; CARD-containing molecule enhancing NF-kappa-B; CARD-containing proapoptotic protein; CED-3/ICH-1 prodomain homologous E10-like regulator; cCARMEN; caspase-recruiting domain-containing protein; cellular homolog of vCARMEN; cellular-E10; hCLAP; mammalian CARD-containing adapter molecule E10 |
Gene ID : | 8915 |
mRNA Refseq : | NM_003921 |
Protein Refseq : | NP_003912 |
MIM : | 603517 |
UniProt ID : | O95999 |
Products Types
◆ Recombinant Protein | ||
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◆ Lysates | ||
BCL10-8490HCL | Recombinant Human BCL10 293 Cell Lysate | +Inquiry |
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For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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