Recombinant Human RXRA, GST-tagged

• Cat.No.: RXRA-119H
• Product Overview: Recombinant Human GST-tagged Retinoid X receptor alpha ligand-binding domain (RXRA-LBD) consists of a 218 a.a. GST tag, a 13 a.a. flexible linker and a 260 a.a. RXRA-LBD, Acc# AAI10999.1, amino acids 203-462 aa, was expressed in baculovirus-infected insect cells and purified using affinity chromatography.

Specification

• Description: Retinoid X receptor alpha (RXR-alpha) is also known as NR2B1 (nuclear receptor subfamily 2, group B, member 1).
• Source: Sf9 insect cells
• Species: Human
• Tag: GST
• Form: 50 mM Tris-HCl pH 8.0, 150 mM NaCl, 3 mM DTT, 7mM reduced glutathione, 0.5 mM EDTA, 20% glycerol.
• Purity: >90%
• Applications: Ligand binding and coactivator peptide recruitment assays.
• Storage: Immediately store at -80℃. Avoid freeze-thaw cycles.While working, please keep sample on ice.

Gene Information

• Gene Name: RXRA retinoid X receptor, alpha [ Homo sapiens ]
• Official Symbol: RXRA
• Synonyms: RXRA; retinoid X receptor, alpha; retinoic acid receptor RXR-alpha; NR2B1; nuclear receptor subfamily 2 group B member 1; retinoid X nuclear receptor alpha; FLJ00280; FLJ00318; FLJ16020; FLJ16733; MGC102720
• Gene ID: 6256
• mRNA Refseq: NM_002957
• Protein Refseq: NP_002948
• MIM: 180245
• UniProt ID: P19793
• Chromosome Location: 9q34
• Pathway: Adipocytokine signaling pathway, organism-specific biosystem; Adipocytokine signaling pathway, conserved biosystem; Adipogenesis, organism-specific biosystem; BMAL1:CLOCK/NPAS2 Activates Circadian Expression, organism-specific biosystem; Bile secretion, organism-specific biosystem; Bile secretion, conserved biosystem; Circadian Clock, organism-specific biosystem
• Function: 9-cis retinoic acid receptor activity; DNA binding; double-stranded DNA binding; enzyme binding; ligand-activated sequence-specific DNA binding RNA polymerase II transcription factor activity; metal ion binding; protein binding; protein heterodimerization activity; receptor activity; retinoic acid receptor activity; retinoic acid-responsive element binding; sequence-specific DNA binding; sequence-specific DNA binding transcription factor activity; contributes_to sequence-specific DNA binding transcription factor activity; steroid binding; steroid hormone receptor activity; transcription coactivator activity; contributes_to transcription regulatory region DNA binding; vitamin D receptor binding; contributes_to vitamin D response element binding; zinc ion binding