Recombinant Human ESR1, GST-tagged ESR1-121H

Recombinant Human ESR1, GST-tagged

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Recombinant Human ESR1, GST-tagged

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Cat.No. : ESR1-121H
Product Overview : Recombinant Human GST-tagged Estrogen receptor alpha ligand-binding domain (ERα-LBD) consists of a 218 a.a. GST tag, a 30 a.a. flexible linker and a 346 a.a. ERα-LBD, Acc# NP_000116 amino acids 250-595, was expressed in baculovirus-infected insect cells and purified using affinity chromatography.
Description : Estrogen receptor alpha (ERα) is also known as NR3A1 (nuclear receptor subfamily 3, group A, member 1).
Source : Sf9 insect cells
Species : Human
Tag : GST
Form : 50 mM Tris-HCl pH 8.0, 150 mM NaCl, 0.5 mM EDTA, 20 mM Na2MoO4, 7 mM reduced glutathione, 20% glycerol.
Purity : >90%
Applications : Ligand binding and coactivator peptide recruitment assays.
Storage : Immediately store at -80℃. Avoid freeze-thaw cycles.While working, please keep sample on ice.
Gene Name : ESR1 estrogen receptor 1 [ Homo sapiens ]
Official Symbol : ESR1
Synonyms : ESR1; estrogen receptor 1; ESR; estrogen receptor; Era; NR3A1; ER-alpha; estradiol receptor; estrogen nuclear receptor alpha; estrogen receptor alpha delta 4 +49 isoform; nuclear receptor subfamily 3 group A member 1; estrogen receptor alpha 3*,4,5,6,7*/822 isoform; estrogen receptor alpha delta 4*,5,6,7*/654 isoform; estrogen receptor alpha delta 4*,5,6,7,8*/901 isoform; estrogen receptor alpha delta 3*,4,5,6,7*/819-2 isoform; estrogen receptor alpha delta 3*,4,5,6,7*,8*/941 isoform; ER; ESRA; DKFZp686N23123;
Gene ID : 2099
mRNA Refseq : NM_000125
Protein Refseq : NP_000116
UniProt ID : P03372
Chromosome Location : 6q24-q27
Pathway : Androgen Receptor Signaling Pathway, organism-specific biosystem; Endocrine and other factor-regulated calcium reabsorption, organism-specific biosystem; Endocrine and other factor-regulated calcium reabsorption, conserved biosystem; Estrogen signaling pathway, organism-specific biosystem; FOXA1 transcription factor network, organism-specific biosystem; FOXM1 transcription factor network, organism-specific biosystem; Gene Expression, organism-specific biosystem;
Function : DNA binding; beta-catenin binding; chromatin binding; core promoter sequence-specific DNA binding; enzyme binding; enzyme binding; estrogen receptor activity; estrogen receptor activity; estrogen response element binding; hormone binding; identical protein binding; ligand-activated sequence-specific DNA binding RNA polymerase II transcription factor activity; metal ion binding; nitric-oxide synthase regulator activity; protein binding; protein complex binding; receptor activity; sequence-specific DNA binding; sequence-specific DNA binding transcription factor activity; sequence-specific DNA binding transcription factor activity; steroid binding; steroid hormone receptor activity; steroid hormone receptor activity; transcription factor binding; type 1 metabotropic glutamate receptor binding; zinc ion binding;

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