Recombinant Human RIOK2, GST-tagged

• Cat.No.: RIOK2-129H
• Product Overview: Full-length recombinant human RIOK2 was expressed by baculovirus in Sf9 insect cells using an N-terminal GST tag.

Specification

• Description: RIOK2 or RIO kinase 2 is a novel cytoplasmic component of pre-40S pre-ribosomal particle(s) in human cells which is required late 40S maturation at several distinct steps. RIOK2 regulates metaphase-anaphase transition during mitotic progression.
• Source: Sf9 insect cells using baculovirus
• Species: Human
• Tag: GST
• Form: 50mM Tris-HCl, pH 7.5, 50mM NaCl, 10mM glutathione, 0.1mM EDTA, 0.25mM DTT, 0.1mM PMSF, 25% glycerol.
• Molecular Mass: ~106 kDa
• AA Sequence: Full Length
• Purity: >95%
• Applications: Western Blot
• Stability: 1 yr at -70°C from date of shipment.
• Storage: Store product at –70oC. For optimal storage, aliquot target into smaller quantities after centrifugation and store at recommended temperature. For most favorable performance, avoid repeated handling and multiple freeze/thaw cycles.
• Concentration: 0.1 ug/ul

Gene Information

• Gene Name: RIOK2 RIO kinase 2 [ Homo sapiens (human) ]
• Official Symbol: RIOK2
• Synonyms: RIO kinase 2 (yeast); serine/threonine-protein kinase RIO2; FLJ11159; EC 2.7.11.1; OTTHUMP00000222868; RIO kinase 2; RIO2; OTTHUMP00000158911
• Gene ID: 55781
• mRNA Refseq: NM_001159749
• Protein Refseq: NP_001153221
• UniProt ID: D6RDI3
• Chromosome Location: 5q15
• Pathway: Ribosome biogenesis in eukaryotes
• Function: ATP binding; protein serine/threonine kinase activity