Native Human AMBP


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Native Human AMBP

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Cat.No. : AMBP-27H
Product Overview : Alpha 1-microglobulin (A1M) is an immunomodulatory protein with a broad spectrum of possible clinical applications and seems a promising marker for evaluation of tubular function. Purified from the urine of patients with chronic renal tubular proteinuria.
Species : Human
Form : Lyophilized from 0.02M NH4HCO3.
Purity : Greater than 96.0%.
Applications : Inhibition of stimulation of cultured lymphocytes by protein antigens; induction of cell division of lymphocytes, a mitogenic effect that can either be enhanced or inhibited by the action of other plasma components; inhibition of neutrophil granulocyte migration in vitro; and inhibition of chemotaxis.
Usage : This product is furnished for LABORATORY RESEARCH USE ONLY. Not for diagnostic or therapeutic use.
Storage : Human A1M although stable at room temperature for 3 weeks, should be stored between 2-8°C.
Reconstitution : Use phosphate buffer, pH>7.0 containing 0.15M NaCl, is recommended.
Gene Name : AMBP alpha-1-microglobulin/bikunin precursor [ Homo sapiens ]
Official Symbol : AMBP
Synonyms : AMBP; alpha-1-microglobulin/bikunin precursor; ITI, ITIL; protein AMBP; bikunin; complex forming glycoprotein heterogeneous in charge; EDC1; growth inhibiting protein 19; HCP; HI30; IATIL; inter alpha trypsin inhibitor light chain; ITILC; protein HC; tryp
Gene ID : 259
mRNA Refseq : NM_001633
Protein Refseq : NP_001624
MIM : 176870
UniProt ID : P02760
Chromosome Location : 9q32-q33
Function : IgA binding; calcium channel inhibitor activity; calcium oxalate binding; heme binding; peptidase inhibitor activity; protein homodimerization activity; serine-type endopeptidase inhibitor activity; transporter activity;

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