Native Human Plasminogen

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Native Human Plasminogen

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Cat.No. : PLG-252H
Description : Found at 12 mg per 100 ml normal plasma. It is the precursor of the serine protease plasmin which s involved in fibrinolysis.
Source : Human Plasma
Species : Human
Form : Lyophilized
Bio-activity : >=120 units/mg protein. One unit is de ned as the amount of enzyme which will hydrolyze 1 μmole of N-tosyl-L-arginine methyl ester in 30 minutes at 37°C at pH 8.0.
Molecular Mass : MW: 90,000 to 92,000
Purity : >95% by SDS-PAGE
Usage : For research or further manufacturing use only.
Quality Control Test : Shown to be non reactive for HBsAg, anti-HCV, anti-HBc, and negative for anti-HIV 1 & 2 by FDA approved tests.
Stability : >1 year
Storage : <=>
Storage Buffer : 20 mM Tris-HCl, pH 7.5, with 2 mM EDTA
Gene Name : PLG plasminogen [ Homo sapiens ]
Official Symbol : PLG
Synonyms : PLG; plasminogen; plasmin; DKFZp779M0222;
Gene ID : 5340
mRNA Refseq : NM_001168338
Protein Refseq : NP_001161810
MIM : 173350
UniProt ID : P00747
Chromosome Location : 6q26
Pathway : Activation of Matrix Metalloproteinases, organism-specific biosystem; Angiopoietin receptor Tie2-mediated signaling, organism-specific biosystem; Blood Clotting Cascade, organism-specific biosystem; Complement and Coagulation Cascades, organism-specific biosystem; Complement and coagulation cascades, organism-specific biosystem; Complement and coagulation cascades, conserved biosystem; Degradation of the extracellular matrix, organism-specific biosystem;
Function : apolipoprotein binding; cell surface binding; peptidase activity; protein binding; protein domain specific binding; serine-type endopeptidase activity;

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