Active Native Human Plasminogen

• Cat.No.: PLG-252H

Specification

• Description: Found at 12 mg per 100 ml normal plasma. It is the precursor of the serine protease plasmin which s involved in fibrinolysis.
• Source: Human Plasma
• Species: Human
• Form: Lyophilized
• Bio-activity: >=120 units/mg protein. One unit is de ned as the amount of enzyme which will hydrolyze 1 μmole of N-tosyl-L-arginine methyl ester in 30 minutes at 37°C at pH 8.0.
• Molecular Mass: MW: 90,000 to 92,000
• Purity: >95% by SDS-PAGE
• Usage: For research or further manufacturing use only.
• Quality Control Test: Shown to be non reactive for HBsAg, anti-HCV, anti-HBc, and negative for anti-HIV 1 & 2 by FDA approved tests.
• Stability: >1 year
• Storage: <=>
• Storage Buffer: 20 mM Tris-HCl, pH 7.5, with 2 mM EDTA

Gene Information

• Gene Name: PLG plasminogen [ Homo sapiens ]
• Official Symbol: PLG
• Synonyms: PLG; plasminogen; plasmin; DKFZp779M0222
• Gene ID: 5340
• mRNA Refseq: NM_001168338
• Protein Refseq: NP_001161810
• MIM: 173350
• UniProt ID: P00747
• Chromosome Location: 6q26
• Pathway: Activation of Matrix Metalloproteinases, organism-specific biosystem; Angiopoietin receptor Tie2-mediated signaling, organism-specific biosystem; Blood Clotting Cascade, organism-specific biosystem; Complement and Coagulation Cascades, organism-specific biosystem; Complement and coagulation cascades, organism-specific biosystem; Complement and coagulation cascades, conserved biosystem; Degradation of the extracellular matrix, organism-specific biosystem
• Function: apolipoprotein binding; cell surface binding; peptidase activity; protein binding; protein domain specific binding; serine-type endopeptidase activity