"MBL2" Related Products

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Recombinant Human MBL2, His-tagged

Cat.No.: MBL2-233H
Product Overview: Recombinant Human MBL /MBL2 Protein (rhMBL / MBL2) Glu 21 - Ile 248 was produced in human 293 cells (HEK293).
Description: This gene encodes the soluble mannose-binding lectin or mannose-binding protein found in serum. The protein encoded belongs to the collectin family and is an important element in the innate immune system. The protein recognizes mannose and N-acetylglucosamine on many microorganisms, and is capable of activating the classical complement pathway. Deficiencies of this gene have been associated with susceptibility to autoimmune and infectious diseases.
Source: HEK293
Species: Human
Tag: His
Form: Lyophilized from 0.22 μm filtered solution in PBS, pH7.4. Normally Mannitol or Trehalose are added as protectants before lyophilization.
Bio-activity: Measured by its ability to bind with Mannan in a functional ELISA.
Molecular Mass: rhMBL / MBL2, fused with 6×His tag at the C-terminus, has a calculated MW of 24.8 kDa. The predicted N-terminus is Glu 21. DTT-reduced Protein migrates as 30-33 kDa.
Endotoxin: Less than 1.0 EU per μg of the rhMBL / MBL2 by the LAL method.
Purity: >95% as determined by SDS-PAGE.
Storage: Avoid repeated freeze-thaw cycles. No activity loss was observed after storage at: In lyophilized state for 1 year (4°C); After reconstitution under sterile conditions for 3 months (-70°C).
Gene Name: MBL2 mannose-binding lectin (protein C) 2, soluble [ Homo sapiens(human) ]
Official Symbol: MBL2
Synonyms: MBL2; MBL; MBP; MBP1; MBPD; MBL2D; MBP-C; COLEC1; HSMBPC; mannose-binding lectin (protein C) 2, soluble; mannose-binding protein C; collectin-1; mannan-binding lectin; mannose-binding lectin 2, soluble (opsonic defect); mannose-binding lectin (protein C) 2, soluble (opsonic defect)
Gene ID: 4153
mRNA Refseq: NM_000242
Protein Refseq: NP_000233
MIM: 154545
UniProt ID: P11226
Chromosome Location: 10q11.2
Pathway: Complement and coagulation cascades; Complement cascade; Immune System
Function: calcium-dependent protein binding; mannose binding; protein binding

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