Recombinant Human TRIM63

• Cat.No.: TRIM63-139H
• Product Overview: Recombinant human TRIM63 (amino acid residues 1-353) was expressed in E.coli.

Specification

• Description: The enzymes of the ubiquitylation pathway play a pivotal role in a number of cellular processes including the regulated and targeted proteasome-dependent degradation of substrate proteins. Three classes of enzymes are involved in the process of ubiquitylation; activating enzymes (E1s), conjugating enzymes (E2s) and protein ligases (E3s). Muscle Ring Finger protein 1 (MuRF1) is a member of the E3 protein ligase family and cloning of the human gene was first described by Dai and Liew et al. (2001).
• Source: E. coli
• Species: Human
• Form: 50mM sodium Bicarbonate pH10, 250mM NaCl, 0.03% Brij35, 0.5mMTCEP
• Molecular Mass: ~40.2kDa
• Purity: >50% by InstantBlue™ SDS-PAGE
• Storage: 12 months at -70°C. Avoid multiple freeze/thaw cycles.
• Concentration: 0.25mg/ml

Gene Information

• Gene Name: TRIM63 tripartite motif containing 63, E3 ubiquitin protein ligase [ Homo sapiens ]
• Official Symbol: TRIM63
• Synonyms: TRIM63; tripartite motif containing 63, E3 ubiquitin protein ligase; ring finger protein 28 , RNF28, tripartite motif containing 63 , tripartite motif containing 63; E3 ubiquitin-protein ligase TRIM63; IRF; iris ring finger protein; MURF 1; muscle specific RING finger protein 1; SMRZ; striated muscle RING zinc finger protein; ring finger protein 28; tripartite motif-containing 63; muscle specific ring finger protein 2; muscle-specific RING finger protein 1; tripartite motif-containing protein 63; MURF1; MURF2; RNF28; FLJ32380
• Gene ID: 84676
• mRNA Refseq: NM_032588
• Protein Refseq: NP_115977
• MIM: 606131
• UniProt ID: Q969Q1
• Chromosome Location: 1p34-p33
• Pathway: Adaptive Immune System, organism-specific biosystem; Antigen processing: Ubiquitination and Proteasome degradation, organism-specific biosystem; Class I MHC mediated antigen processing & presentation, organism-specific biosystem; Immune System, organism-specific biosystem
• Function: ligase activity; metal ion binding; signal transducer activity; titin binding; ubiquitin-protein ligase activity; zinc ion binding